Publications

2020

Armstrong EC, Caruso A, Servadio M, Andreae LC, Trezza V, Scattoni ML, Fernandes C (2020) Assessing the developmental trajectory of mouse models of neurodevelopmental disorders: Social and communication deficits in mice with Neurexin 1α deletion. Genes Brain Behav 19: e12630
Ramos SI, Makeyev EV, Salierno M, Kodama T, Kawakami Y, Sahara S (2020) Tuba8 Drives Differentiation of Cortical Radial Glia into Apical Intermediate Progenitors by Tuning Modifications of Tubulin C Termini. Dev Cell 52: 477-491.e8
Sahara S, Kodama T, Stevens CF (2020) A common rule governing differentiation kinetics of mouse cortical progenitors. Proc Natl Acad Sci U S A 117: 15221-15229

2019

Minichino A, Rutigliano G, Merlino S, Davies C, Oliver D, De Micheli A, Patel R, McGuire P, Fusar-Poli P (2019) Unmet needs in patients with brief psychotic disorders: Too ill for clinical high risk services and not ill enough for first episode services. Eur Psychiatry 57: 26-32

Favuzzi E, Deogracias R, Marques-Smith A, Maeso P, Jezequel J, Exposito-Alonso D, Balia M, Kroon T, Hinojosa AJ, F Maraver E, Rico B (2019) Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits. Science 363: 413-417

Pretzsch CM, Freyberg J, Voinescu B, Lythgoe D, Horder J, Mendez MA, Wichers R, Ajram L, Ivin G, Heasman M, Edden RAE, Williams S, Murphy DGM, Daly E, McAlonan GM (2019) Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder. Neuropsychopharmacology

Colizzi M, Weltens N, McGuire P, Lythgoe D, Williams S, Van Oudenhove L, Bhattacharyya S (2019) Delta-9-tetrahydrocannabinol increases striatal glutamate levels in healthy individuals: implications for psychosis. Mol Psychiatry

Pote I, Wang S, Sethna V, Blasi A, Daly E, Kuklisova-Murgasova M, Lloyd-Fox S, Mercure E, Busuulwa P, Stoencheva V, Charman T, Williams SCR, Johnson MH, Murphy DGM, McAlonan GM (2019) Familial risk of autism alters subcortical and cerebellar brain anatomy in infants and predicts the emergence of repetitive behaviors in early childhood. Autism Res

Pervolaraki E, Tyson AL, Pibiri F, Poulter SL, Reichelt AC, Rodgers RJ, Clapcote SJ, Lever C, Andreae LC, Dachtler J (2019) The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice Mol Autism 10: 8
Liao M, Kundap U, Rosch RE, Burrows DRW, Meyer MP, Bouchra BOA, Cossette P, Samarut É (2019) Targeted knockout of GABA receptor gamma 2 subunit provokes transient light-induced reflex seizures in zebrafish larvae. Dis Model Mech

Diana G, Sainsbury TTJ, Meyer MP (2019) Bayesian inference of neuronal assemblies. PLoS Comput Biol 15: e1007481
Llorca A, Ciceri G, Beattie R, Wong FK, Diana G, Serafeimidou-Pouliou E, Fernández-Otero M, Streicher C, Arnold SJ, Meyer M, Hippenmeyer S, Maravall M, Marin O (2019) A stochastic framework of neurogenesis underlies the assembly of neocortical cytoarchitecture. Elife 8
Johansson M, Giger FA, Fielding T, Houart C (2019) Dkk1 Controls Cell-Cell Interaction through Regulation of Non-nuclear Beta-Catenin Pools. Dev Cell 51: 775-786.e3

2018

Basil, P., Li, Q., Gui, H., Hui, T. C. K., Man, V. L. H., Wong, C. C. Y.,Jonathan Mill, Grainne M. McAlonan & Pak-Chung Sham (2018) Prenatal immune activation alters the adult neural epigenome but can be partly stabilized by a n-3 polyunsaturated fatty acid diet Translational Psychiatryvolume 8

O'Muircheartaigh J, Jbabdi S (2018) Concurrent white matter bundles and grey matter networks using independent component analysis. Neuroimage 170: 296-306
Kathuria A, Nowosiad P, Jagasia R, Aigner S, Taylor RD, Andreae LC, Gatford NJF, Lucchesi W, Srivastava DP, Price J (2018) Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development. Mol Psychiatry 23: 735-746

Andreae LC, Burrone J (2018) The role of spontaneous neurotransmission in synapse and circuit development. J Neurosci Res 96: 354-359

Del Pino I, Rico B, Marín O (2018) Neural circuit dysfunction in mouse models of neurodevelopmental disorders. Curr Opin Neurobiol 48: 174-182
Oliver D, Kotlicka-Antczak M, Minichino A, Spada G, McGuire P, Fusar-Poli P (2018) Meta-analytical prognostic accuracy of the Comprehensive Assessment of at Risk Mental States (CAARMS): The need for refined prediction. Eur Psychiatry 49: 62-68
Orlov ND, Giampietro V, O'Daly O, Lam SL, Barker GJ, Rubia K, McGuire P, Shergill SS, Allen P (2018) Real-time fMRI neurofeedback to down-regulate superior temporal gyrus activity in patients with schizophrenia and auditory hallucinations: a proof-of-concept study. Transl Psychiatry 8: 46
Bossong MG, Wilson R, Appiah-Kusi E, McGuire P, Bhattacharyya S (2018) Human striatal response to reward anticipation linked to hippocampal glutamate levels. Int J Neuropsychopharmacol
Pollak TA, Rogers JP, Nagele RG, Peakman M, Stone JM, David AS, McGuire P (2018) Antibodies in the Diagnosis, Prognosis, and Prediction of Psychotic Disorders. Schizophr Bull
Andrews DS, Marquand A, Ecker C, McAlonan G (2018) Using Pattern Classification to Identify Brain Imaging Markers in Autism Spectrum Disorder. Curr Top Behav Neurosci
Favuzzi E, Rico B (2018) Molecular diversity underlying cortical excitatory and inhibitory synapse development. Curr Opin Neurobiol 53: 8-15
Hinojosa AJ, Deogracias R, Rico B (2018) The Microtubule Regulator NEK7 Coordinates the Wiring of Cortical Parvalbumin Interneurons. Cell Rep 24: 1231-1242
Rosch RE, Hunter PR, Baldeweg T, Friston KJ, Meyer MP (2018) Calcium imaging and dynamic causal modelling reveal brain-wide changes in effective connectivity and synaptic dynamics during epileptic seizures. PLoS Comput Biol 14: e1006375
Murray KN, Edye ME, Manca M, Vernon AC, Oladipo JM, Fasolino V, Harte MK, Mason V, Grayson B, McHugh PC, Knuesel I, Prinssen EP, Hager R, Neill JC (2018) Evolution of a maternal immune activation (mIA) model in rats: Early developmental effects. Brain Behav Immun
Ajram LA, Pereira AC, Durieux AMS, Velthius HE, Petrinovic MM, McAlonan GM (2018) The contribution of [1H] magnetic resonance spectroscopy to the study of excitation-inhibition in autism. Prog Neuropsychopharmacol Biol Psychiatry 89: 236-244
Modinos G, ?im?ek F, Azis M, Bossong M, Bonoldi I, Samson C, Quinn B, Perez J, Broome MR, Zelaya F, Lythgoe DJ, Howes OD, Stone JM, Grace AA, Allen P, McGuire P (2018) Correction: Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis. Neuropsychopharmacology 43: 2660
Tiwari N, Pataskar A, Péron S, Thakurela S, Sahu SK, Figueres-Oñate M, Marichal N, López-Mascaraque L, Tiwari VK, Berninger B (2018) Stage-Specific Transcription Factors Drive Astrogliogenesis by Remodeling Gene Regulatory Landscapes. Cell Stem Cell 23: 557-571.e8
Kravariti E, Reeve-Mates C, Da Gama Pires R, Tsakanikos E, Hayes D, Renshaw S, McAllister S, Bhavsar V, Patterson P, Daley E, Stewart J, Pritchard M, Shetty H, Ramsay R, Perez-Iglesias R, McGuire P (2018) Effectiveness of automated appointment reminders in Psychosis Community Services: A randomised controlled trial - CORRIGENDUM. BJPsych Open 4: 419
Zimmermann T, Maroso M, Beer A, Baddenhausen S, Ludewig S, Fan W, Vennin C, Loch S, Berninger B, Hofmann C, Korte M, Soltesz I, Lutz B, Leschik J (2018) Neural stem cell lineage-specific cannabinoid type-1 receptor regulates neurogenesis and plasticity in the adult mouse hippocampus. Cereb Cortex 28: 4454-4471
Lim L, Mi D, Llorca A, Marín O (2018) Development and Functional Diversification of Cortical Interneurons. Neuron 100: 294-313
Sato JR, Biazoli CE, Salum GA, Gadelha A, Crossley N, Vieira G, Zugman A, Picon FA, Pan PM, Hoexter MQ, Amaro E, Anés M, Moura LM, Del'Aquilla MAG, Mcguire P, Rohde LA, Miguel EC, Bressan RA, Jackowski AP (2018) Associations between children's family environment, spontaneous brain oscillations, and emotional and behavioral problems. Eur Child Adolesc Psychiatry
Bossong MG, Antoniades M, Azis M, Samson C, Quinn B, Bonoldi I, Modinos G, Perez J, Howes OD, Stone JM, Allen P, McGuire P (2018) Association of Hippocampal Glutamate Levels With Adverse Outcomes in Individuals at Clinical High Risk for Psychosis. JAMA Psychiatry
Antony AR, Abramovici S, Krafty RT, Pan J, Richardson M, Bagic A, Haneef Z (2018) Simultaneous scalp EEG improves seizure lateralization during unilateral intracranial EEG evaluation in temporal lobe epilepsy. Seizure 64: 8-15
Taylor RD, Heine M, Emptage NJ, Andreae LC (2018) Neuronal Receptors Display Cytoskeleton-Independent Directed Motion on the Plasma Membrane. iScience 10: 234-244
Lipovsek M, Wingate RJ (2018) Conserved and divergent development of brainstem vestibular and auditory nuclei. Elife 7
Mars RB, O'Muircheartaigh J, Folloni D, Li L, Glasser MF, Jbabdi S, Bryant KL (2018) Concurrent analysis of white matter bundles and grey matter networks in the chimpanzee. Brain Struct Funct

2017

Deans PJM, Raval P, Sellers KJ, Gatford NJF, Halai S, Duarte RRR, Shum C, Warre-Cornish K, Kaplun VE, Cocks G, Hill M, Bray NJ, Price J, Srivastava DP (2017) Psychosis Risk Candidate ZNF804A Localizes to Synapses and Regulates Neurite Formation and Dendritic Spine Structure. Biol Psychiatry 82: 49-61
Crum WR, Sawiak SJ, Chege W, Cooper JD, Williams SCR, Vernon AC (2017) Evolution of structural abnormalities in the rat brain following in utero exposure to maternal immune activation: A longitudinal in vivo MRI study. Brain Behav Immun 63: 50-59
Dehorter N, Marichal N, Marín O, Berninger B (2017) Tuning neural circuits by turning the interneuron knob. Curr Opin Neurobiol 42: 144-151
Bielen H, Pal S, Tole S, Houart C (2017) Temporal variations in early developmental decisions: an engine of forebrain evolution. Curr Opin Neurobiol 42: 152-159
Notter T, Coughlin JM, Gschwind T, Weber-Stadlbauer U, Wang Y, Kassiou M, Vernon AC, Benke D, Pomper MG, Sawa A, Meyer U (2017) Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia. Mol Psychiatry
Bartolini G, Sánchez-Alcañiz JA, Osório C, Valiente M, García-Frigola C, Marín O (2017) Neuregulin 3 Mediates Cortical Plate Invasion and Laminar Allocation of GABAergic Interneurons. Cell Rep 18: 1157-1170
Walker AS, Neves G, Grillo F, Jackson RE, Rigby M, O'Donnell C, Lowe AS, Vizcay-Barrena G, Fleck RA, Burrone J (2017) Distance-dependent gradient in NMDAR-driven spine calcium signals along tapering dendrites. Proc Natl Acad Sci U S A 114: E1986-E1995
Addis L, Virdee JK, Vidler LR, Collier DA, Pal DK, Ursu D (2017) Epilepsy-associated GRIN2A mutations reduce NMDA receptor trafficking and agonist potency - molecular profiling and functional rescue. Sci Rep 7: 66
Glebov OO, Jackson RE, Winterflood CM, Owen DM, Barker EA, Doherty P, Ewers H, Burrone J (2017) Nanoscale Structural Plasticity of the Active Zone Matrix Modulates Presynaptic Function. Cell Rep 18: 2715-2728
Ingham NJ, Steel KP, Drescher U (2017) On the role of ephrinA2 in auditory function. Hear Res 350: 11-16

Del Pino I, Brotons-Mas JR, Marques-Smith A, Marighetto A, Frick A, Marín O, Rico B (2017) Abnormal wiring of CCK Nat Neurosci 20: 784-792

Stockley JH, Evans K, Matthey M, Volbracht K, Agathou S, Mukanowa J, Burrone J, Káradóttir RT (2017) Surpassing light-induced cell damage in vitro with novel cell culture media. Sci Rep 7: 849

Janecka M, Haworth CMA, Ronald A, Krapohl E, Happé F, Mill J, Schalkwyk LC, Fernandes C, Reichenberg A, Rijsdijk F (2017) Paternal Age Alters Social Development in Offspring. J Am Acad Child Adolesc Psychiatry 56: 383-390
Egeland M, Guinaudie C, Du Preez A, Musaelyan K, Zunszain PA, Fernandes C, Pariante CM, Thuret S (2017) Depletion of adult neurogenesis using the chemotherapy drug temozolomide in mice induces behavioural and biological changes relevant to depression. Transl Psychiatry 7: e1101
Mondelli V, Vernon AC, Turkheimer F, Dazzan P, Pariante CM (2017) Brain microglia in psychiatric disorders. Lancet Psychiatry 4: 563-572
Ajram LA, Horder J, Mendez MA, Galanopoulos A, Brennan LP, Wichers RH, Robertson DM, Murphy CM, Zinkstok J, Ivin G, Heasman M, Meek D, Tricklebank MD, Barker GJ, Lythgoe DJ, Edden RAE, Williams SC, Murphy DGM, McAlonan GM (2017) Shifting brain inhibitory balance and connectivity of the prefrontal cortex of adults with autism spectrum disorder. Transl Psychiatry 7: e1137
Ecker C, Schmeisser MJ, Loth E, Murphy DG (2017) Neuroanatomy and Neuropathology of Autism Spectrum Disorder in Humans. Adv Anat Embryol Cell Biol 224: 27-48
Smith AB, Dawes P, Smith S, Pal DK (2017) A specific deficit of auditory processing in children with Rolandic Epilepsy and their relatives. Epilepsy Behav 72: 135-139
Favuzzi E, Marques-Smith A, Deogracias R, Winterflood CM, Sánchez-Aguilera A, Mantoan L, Maeso P, Fernandes C, Ewers H, Rico B (2017) Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican. Neuron 95: 639-655.e10
Ball G, Aljabar P, Nongena P, Kennea N, Gonzalez-Cinca N, Falconer S, Chew ATM, Harper N, Wurie J, Rutherford MA, Counsell SJ, Edwards AD (2017) Multimodal image analysis of clinical influences on preterm brain development. Ann Neurol 82: 233-246
Edwards AD, Redshaw ME, Kennea N, Rivero-Arias O, Gonzales-Cinca N, Nongena P, Ederies M, Falconer S, Chew A, Omar O, Hardy P, Harvey ME, Eddama O, Hayward N, Wurie J, Azzopardi D, Rutherford MA, Counsell S (2017) Effect of MRI on preterm infants and their families: a randomised trial with nested diagnostic and economic evaluation. Arch Dis Child Fetal Neonatal Ed
Tusor N, Benders MJ, Counsell SJ, Nongena P, Ederies MA, Falconer S, Chew A, Gonzalez-Cinca N, Hajnal JV, Gangadharan S, Chatzi V, Kersbergen KJ, Kennea N, Azzopardi DV, Edwards AD (2017) Punctate White Matter Lesions Associated With Altered Brain Development And Adverse Motor Outcome In Preterm Infants. Sci Rep 7: 13250
Patel R, Chesney E, Taylor M, Taylor D, McGuire P (2017) Is paliperidone palmitate more effective than other long-acting injectable antipsychotics? Psychol Med : 1-10

Carlisi CO, Norman L, Murphy CM, Christakou A, Chantiluke K, Giampietro V, Simmons A, Brammer M, Murphy DG, Mataix-Cols D, Rubia K (2017) Shared and Disorder-Specific Neurocomputational Mechanisms of Decision-Making in Autism Spectrum Disorder and Obsessive-Compulsive Disorder. Cereb Cortex 27: 5804-5816

Donovan APA, Yu T, Ellegood J, Riegman KLH, de Geus C, van Ravenswaaij-Arts C, Fernandes C, Lerch JP, Basson MA (2017) Cerebellar Vermis and Midbrain Hypoplasia Upon Conditional Deletion of Chd7 from the Embryonic Mid-Hindbrain Region. Front Neuroanat 11: 86

Jauhar S, Nour MM, Veronese M, Rogdaki M, Bonoldi I, Azis M, Turkheimer F, McGuire P, Young AH, Howes OD (2017) A Test of the Transdiagnostic Dopamine Hypothesis of Psychosis Using Positron Emission Tomographic Imaging in Bipolar Affective Disorder and Schizophrenia. JAMA Psychiatry 74: 1206-1213

Hawkins PCT, Wood TC, Vernon AC, Bertolino A, Sambataro F, Dukart J, Merlo-Pich E, Risterucci C, Silber-Baumann H, Walsh E, Mazibuko N, Zelaya FO, Mehta MA (2017) An investigation of regional cerebral blood flow and tissue structure changes after acute administration of antipsychotics in healthy male volunteers. Hum Brain Mapp 39: 319-331

McCutcheon R, Beck K, D'Ambrosio E, Donocik J, Gobjila C, Jauhar S, Kaar S, Pillinger T, Reis Marques T, Rogdaki M, Howes OD (2017) Antipsychotic plasma levels in the assessment of poor treatment response in schizophrenia. Acta Psychiatr Scand

Bhattacharyya S, Egerton A, Kim E, Rosso L, Riano Barros D, Hammers A, Brammer M, Turkheimer FE, Howes OD, McGuire P (2017) Acute induction of anxiety in humans by delta-9-tetrahydrocannabinol related to amygdalar cannabinoid-1 (CB1) receptors. Sci Rep 7: 15025

Shakoor S, McGuire P, Cardno AG, Freeman D, Ronald A (2017) A twin study exploring the association between childhood emotional and behaviour problems and specific psychotic experiences in a community sample of adolescents. J Child Psychol Psychiatry

Furlan G, Cuccioli V, Vuillemin N, Dirian L, Muntasell AJ, Coolen M, Dray N, Bedu S, Houart C, Beaurepaire E, Foucher I, Bally-Cuif L (2017) Life-Long Neurogenic Activity of Individual Neural Stem Cells and Continuous Growth Establish an Outside-In Architecture in the Teleost Pallium. Curr Biol 27: 3288-3301.e3

Perani S, Tierney TM, Centeno M, Shamshiri EA, Yaakub SN, O'Muircheartaigh J, Carmichael DW, Richardson MP (2017) Thalamic volume reduction in drug-naive patients with new-onset genetic generalized epilepsy. Epilepsia

Carlisi CO, Norman L, Murphy CM, Christakou A, Chantiluke K, Giampietro V, Simmons A, Brammer M, Murphy DG, Mataix-Cols D, Rubia K (2017) Disorder-Specific and Shared Brain Abnormalities During Vigilance in Autism and Obsessive-Compulsive Disorder. Biol Psychiatry Cogn Neurosci Neuroimaging 2: 644-654

Whittaker DE, Kasah S, Donovan APA, Ellegood J, Riegman KLH, Volk HA, McGonnell I, Lerch JP, Basson MA (2017) Distinct cerebellar foliation anomalies in a CHD7 haploinsufficient mouse model of CHARGE syndrome. Am J Med Genet C Semin Med Genet 175

Froudist-Walsh S, Bloomfield MA, Veronese M, Kroll J, Karolis VR, Jauhar S, Bonoldi I, McGuire PK, Kapur S, Murray RM, Nosarti C, Howes O (2017) The effect of perinatal brain injury on dopaminergic function and hippocampal volume in adult life. Elife 6

Morris C, Dunkley C, Gibbon FM, Currier J, Roberts D, Rogers M, Crudgington H, Bray L, Carter B, Hughes D, Tudur Smith C, Williamson PR, Gringras P, Pal DK (2017) Core Health Outcomes In Childhood Epilepsy (CHOICE): protocol for the selection of a core outcome set. Trials 18: 572

Abbas F, Triplett MA, Goodhill GJ, Meyer MP (2017) A Three-Layer Network Model of Direction Selective Circuits in the Optic Tectum. Front Neural Circuits 11: 88

Lee J, Kim BH, Kim E, Howes OD, Cho KIK, Yoon YB, Kwon JS (2017) Higher serotonin transporter availability in early-onset obsessive-compulsive disorder patients undergoing escitalopram treatment: A [11 C]DASB PET study. Hum Psychopharmacol

Krishnan ML, Wang Z, Aljabar P, Ball G, Mirza G, Saxena A, Counsell SJ, Hajnal JV, Montana G, Edwards AD (2017) Machine learning shows association between genetic variability in PPARG and cerebral connectivity in preterm infants. Proc Natl Acad Sci U S A 114: 13744-13749

McGuire P, Robson P, Cubala WJ, Vasile D, Morrison PD, Barron R, Taylor A, Wright S (2017) Cannabidiol (CBD) as an Adjunctive Therapy in Schizophrenia: A Multicenter Randomized Controlled Trial. Am J Psychiatry : appiajp201717030325

2016

Delbaere J, Van Herck SL, Bourgeois NM, Vancamp P, Yang S, Wingate RJ, Darras VM (2016) Mosaic Expression of Thyroid Hormone Regulatory Genes Defines Cell Type-Specific Dependency in the Developing Chicken Cerebellum. Cerebellum 15: 710-725
Kawaguchi D, Sahara S, Zembrzycki A, O'Leary DDM (2016) Generation and analysis of an improved Foxg1-IRES-Cre driver mouse line. Dev Biol 412: 139-147

Glebov OO, Cox S, Humphreys L, Burrone J (2016) Neuronal activity controls transsynaptic geometry. Sci Rep 6: 22703
Duarte RRR, Troakes C, Nolan M, Srivastava DP, Murray RM, Bray NJ (2016) Genome-wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis-regulation of BORCS7, AS3MT, and NT5C2 in the human brain. Am J Med Genet B Neuropsychiatr Genet 171: 806-14
Antinucci P, Suleyman O, Monfries C, Hindges R (2016) Neural Mechanisms Generating Orientation Selectivity in the Retina. Curr Biol 26: 1802-15
Antinucci P, Hindges R (2016) A crystal-clear zebrafish for in vivo imaging. Sci Rep 6: 29490
Jackson RE, Burrone J (2016) Visualizing Presynaptic Calcium Dynamics and Vesicle Fusion with a Single Genetically Encoded Reporter at Individual Synapses. Front Synaptic Neurosci 8: 21
Donovan AP, Basson MA (2016) The neuroanatomy of autism - a developmental perspective. J Anat
Wefelmeyer W, Puhl CJ, Burrone J (2016) Homeostatic Plasticity of Subcellular Neuronal Structures: From Inputs to Outputs. Trends Neurosci 39: 656-667
Marín O (2016) Developmental timing and critical windows for the treatment of psychiatric disorders. Nat Med 22: 1229-1238
Marques-Smith A, Favuzzi E, Rico B (2016) Shaping Early Networks to Rule Mature Circuits: Little MiRs Go a Long Way. Neuron 92: 1154-1157