Anderson GW, Deans PJ, Taylor RD, Raval P, Chen D, Lowder H, Murkerji S, Andreae LC, Williams BP, Srivastava DP (2015) Characterisation of neurons derived from a cortical human neural stem cell line CTX0E16. Stem Cell Res Ther 6: 149

Taken together, these findings demonstrate that the CTX0E16 hNPC line is a robust source of cortical neurons, which display functional properties consistent with a glutamatergic phenotype. Thus CTX0E16 neurons can be used to study cortical cell function, and furthermore, as these neurons express a range of disease-associated genes, they represent an ideal platform with which to investigate neurodevelopmental mechanisms in native human cells in health and disease.

Pubmed: 26296747