Publications

2015

Chen G, Wernig M, Berninger B, Nakafuku M, Parmar M, Zhang CL (2015) In Vivo Reprogramming for Brain and Spinal Cord Repair. eNeuro 2(5): 0106-15.20
Anderson GW, Deans PJ, Taylor RD, Raval P, Chen D, Lowder H, Murkerji S, Andreae LC, Williams BP, Srivastava DP (2015) Characterisation of neurons derived from a cortical human neural stem cell line CTX0E16. Stem Cell Res Ther 6: 149
Poort J, Khan AG, Pachitariu M, Nemri A, Orsolic I, Krupic J, Bauza M, Sahani M, Keller GB, Mrsic-Flogel TD, Hofer SB (2015) Learning Enhances Sensory and Multiple Non-sensory Representations in Primary Visual Cortex. Neuron 86: 1478-90

Hannon E, Chand AN, Evans MD, Wong CC, Grubb MS, Mill J (2015) A role for CaV1 and calcineurin signaling in depolarization-induced changes in neuronal DNA methylation. Neuroepigenetics 3: 1-6
Mockenhaupt S, Makeyev EV (2015) Non-coding functions of alternative pre-mRNA splicing in development. Semin Cell Dev Biol 47-48: 32-9
Nikolaou N, Meyer MP (2015) Neurobiology: imaging prey capture circuits in zebrafish. Curr Biol 25: R273-5
Hanzel M, Wingate RJ, Butts T (2015) Ex Vivo Culture of Chick Cerebellar Slices and Spatially Targeted Electroporation of Granule Cell Precursors. J Vis Exp 106: e53421

Zembrzycki A, Stocker AM, Leingärtner A, Sahara S, Chou SJ, Kalatsky V, May SR, Stryker MP, O'Leary DD (2015) Genetic mechanisms control the linear scaling between related cortical primary and higher order sensory areas. Elife 4

An W, Jackson RE, Hunter P, Gögel S, van Diepen M, Liu K, Meyer MP, Eickholt BJ (2015) Engineering FKBP-Based Destabilizing Domains to Build Sophisticated Protein Regulation Systems. PLoS One 10: e0145783
Wasserman SM, Aptekar JW, Lu P, Nguyen J, Wang AL, Keles MF, Grygoruk A, Krantz DE, Larsen C, Frye MA (2015) Olfactory neuromodulation of motion vision circuitry in Drosophila. Curr Biol 25: 467-72
Slater G, Levy P, Chan KL, Larsen C (2015) A central neural pathway controlling odor tracking in Drosophila. J Neurosci 35: 1831-48
Nikolaou N, Meyer MP (2015) Lamination Speeds the Functional Development of Visual Circuits. Neuron 88: 999-1013
Loncle N, Agromayor M, Martin-Serrano J, Williams DW (2015) An ESCRT module is required for neuron pruning. Sci Rep 5: 8461
Wefelmeyer W, Cattaert D, Burrone J (2015) Activity-dependent mismatch between axo-axonic synapses and the axon initial segment controls neuronal output. Proc Natl Acad Sci U S A 112: 9757-62
Patel AX, Burdakov D (2015) Mechanisms of gain control by voltage-gated channels in intrinsically-firing neurons. PLoS One 10: e0115431
Dai W, Li W, Hoque M, Li Z, Tian B, Makeyev EV (2015) A post-transcriptional mechanism pacing expression of neural genes with precursor cell differentiation status. Nat Commun 6: 7576
Apergis-Schoute J, Iordanidou P, Faure C, Jego S, Schöne C, Aitta-Aho T, Adamantidis A, Burdakov D (2015) Optogenetic evidence for inhibitory signaling from orexin to MCH neurons via local microcircuits. J Neurosci 35: 5435-41
Chand AN, Galliano E, Chesters RA, Grubb MS (2015) A distinct subtype of dopaminergic interneuron displays inverted structural plasticity at the axon initial segment. J Neurosci 35: 1573-90
Tyson AL, Hilton ST, Andreae LC (2015) Rapid, simple and inexpensive production of custom 3D printed equipment for large-volume fluorescence microscopy. Int J Pharm 494: 651-6
Missaire M, Hindges R (2015) The role of cell adhesion molecules in visual circuit formation: from neurite outgrowth to maps and synaptic specificity. Dev Neurobiol 75: 569-83
Hunter PR, Hendry AC, Lowe AS (2015) Zebrafish brain mapping--standardized spaces, length scales, and the power of N and n. Dev Neurobiol 75: 557-68
Evans MD, Dumitrescu AS, Kruijssen DL, Taylor SE, Grubb MS (2015) Rapid Modulation of Axon Initial Segment Length Influences Repetitive Spike Firing. Cell Rep 13: 1233-45
Andreae LC, Burrone J (2015) Spontaneous Neurotransmitter Release Shapes Dendritic Arbors via Long-Range Activation of NMDA Receptors. Cell Rep 15: S2211-1247

Entchev EV, Patel DS, Zhan M, Steele AJ, Lu H, Ch'ng Q (2015) A gene-expression-based neural code for food abundance that modulates lifespan. Elife 4: e06259
Dehorter N, Ciceri G, Bartolini G, Lim L, del Pino I, Marín O (2015) Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch. Science 349: 1216-20

Sonego M, Oberoi M, Stoddart J, Gajendra S, Hendricusdottir R, Oozeer F, Worth DC, Hobbs C, Eickholt BJ, Gordon-Weeks PR, Doherty P, Lalli G (2015) Drebrin regulates neuroblast migration in the postnatal Mammalian brain. PLoS One 10: e0126478

2014

Irimia M, Weatheritt RJ, Ellis JD, Parikshak NN, Gonatopoulos-Pournatzis T, Babor M, Quesnel-Vallières M, Tapial J, Raj B, O'Hanlon D, Barrios-Rodiles M, Sternberg MJ, Cordes SP, Roth FP, Wrana JL, Geschwind DH, Blencowe BJ (2014) A highly conserved program of neuronal microexons is misregulated in autistic brains. Cell 159: 1511-23
Nelson AC, Cutty SJ, Niini M, Stemple DL, Flicek P, Houart C, Bruce AE, Wardle FC (2014) Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression. BMC Biol 12: 81
Long KR, Ffrench-Constant C (2014) Neural stem cell quiescence comes to an un-sticky end. Nat Cell Biol 16: 625-7
Arlotta P, Berninger B (2014) Brains in metamorphosis: reprogramming cell identity within the central nervous system. Curr Opin Neurobiol 27: 208-14
Karow M, Schichor C, Beckervordersandforth R, Berninger B (2014) Lineage-reprogramming of pericyte-derived cells of the adult human brain into induced neurons. J Vis Exp
Heinrich C, Bergami M, Gascón S, Lepier A, Viganò F, Dimou L, Sutor B, Berninger B, Götz M (2014) Sox2-mediated conversion of NG2 glia into induced neurons in the injured adult cerebral cortex. Stem Cell Reports 3: 1000-14
Andreae LC, Burrone J (2014) The role of neuronal activity and transmitter release on synapse formation. Curr Opin Neurobiol 27: 47-52
Buckley C, Clarke J (2014) Establishing the plane of symmetry for lumen formation and bilateral brain formation in the zebrafish neural rod. Semin Cell Dev Biol 31: 100-5
Zakaria S, Mao Y, Kuta A, de Sousa CF, Gaufo GO, McNeill H, Hindges R, Guthrie S, Irvine KD, Francis-West PH (2014) Regulation of neuronal migration by Dchs1-Fat4 planar cell polarity. Curr Biol 24: 1620-1627
Astick M, Tubby K, Mubarak WM, Guthrie S, Price SR (2014) Central topography of cranial motor nuclei controlled by differential cadherin expression. Curr Biol 24: 2541-7
Neo WH, Yap K, Lee SH, Looi LS, Khandelia P, Neo SX, Makeyev EV, Su IH (2014) MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression. J Biol Chem 289: 20788-801
Jain N, Lim LW, Tan WT, George B, Makeyev E, Thanabalu T (2014) Conditional N-WASP knockout in mouse brain implicates actin cytoskeleton regulation in hydrocephalus pathology. Exp Neurol 254: 29-40
Abbas F, Meyer MP (2014) Fish vision: size selectivity in the zebrafish retinotectal pathway. Curr Biol 24: R1048-50
Kosse C, Burdakov D (2014) A unifying computational framework for stability and flexibility of arousal. Front Syst Neurosci 8: 192
Marklund U, Alekseenko Z, Andersson E, Falci S, Westgren M, Perlmann T, Graham A, Sundström E, Ericson J (2014) Detailed expression analysis of regulatory genes in the early developing human neural tube. Stem Cells Dev 23: 5-15
Dyer C, Linker C, Graham A, Knight R (2014) Specification of sensory neurons occurs through diverse developmental programs functioning in the brain and spinal cord. Dev Dyn 243: 1429-39
Aigner S, Heckel T, Zhang JD, Andreae LC, Jagasia R (2014) Human pluripotent stem cell models of autism spectrum disorder: emerging frontiers, opportunities, and challenges towards neuronal networks in a dish. Psychopharmacology (Berl) 231: 1089-104
Hamid FM, Makeyev EV (2014) Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5' splice site choice. PLoS Genet 10: e1004771
Tripathi VB, Baskaran P, Shaw CE, Guthrie S (2014) Tar DNA-binding protein-43 (TDP-43) regulates axon growth in vitro and in vivo. Neurobiol Dis 65: 25-34
Araya C, Tawk M, Girdler GC, Costa M, Carmona-Fontaine C, Clarke JD (2014) Mesoderm is required for coordinated cell movements within zebrafish neural plate in vivo. Neural Dev 9: 9
Shone V, Graham A (2014) Endodermal/ectodermal interfaces during pharyngeal segmentation in vertebrates. J Anat 225: 479-91
Graham A, Butts T, Lumsden A, Kiecker C (2014) What can vertebrates tell us about segmentation? Evodevo 5: 24
Schöne C, Apergis-Schoute J, Sakurai T, Adamantidis A, Burdakov D (2014) Coreleased orexin and glutamate evoke nonredundant spike outputs and computations in histamine neurons. Cell Rep 7: 697-704
Povellato G, Tuxworth RI, Hanger DP, Tear G (2014) Modification of the Drosophila model of in vivo Tau toxicity reveals protective phosphorylation by GSK3b. Biol Open 3: 1-11
Hamid FM, Makeyev EV (2014) Emerging functions of alternative splicing coupled with nonsense-mediated decay. Biochem Soc Trans 42: 1168-73
Butts T, Green MJ, Wingate RJ (2014) Development of the cerebellum: simple steps to make a 'little brain'. Development 141: 4031-41
Butts T, Modrell MS, Baker CV, Wingate RJ (2014) The evolution of the vertebrate cerebellum: absence of a proliferative external granule layer in a non-teleost ray-finned fish. Evol Dev 16: 92-100
Butts T, Hanzel M, Wingate RJ (2014) Transit amplification in the amniote cerebellum evolved via a heterochronic shift in NeuroD1 expression. Development 141: 2791-5
Green MJ, Wingate RJ (2014) Developmental origins of diversity in cerebellar output nuclei. Neural Dev 9: 1
Bryson JB, Machado CB, Crossley M, Stevenson D, Bros-Facer V, Burrone J, Greensmith L, Lieberam I (2014) Optical control of muscle function by transplantation of stem cell-derived motor neurons in mice. Science 344: 94-7
Marler KJ, Suetterlin P, Dopplapudi A, Rubikaite A, Adnan J, Maiorano NA, Lowe AS, Thompson ID, Pathania M, Bordey A, Fulga T, Van Vactor DL, Hindges R, Drescher U (2014) BDNF promotes axon branching of retinal ganglion cells via miRNA-132 and p250GAP. J Neurosci 34: 969-79

Suetterlin P, Drescher U (2014) Target-independent ephrina/EphA-mediated axon-axon repulsion as a novel element in retinocollicular mapping. Neuron 84: 740-52

Pereira Dias G, Hollywood R, Bevilaqua MC, da Luz AC, Hindges R, Nardi AE, Thuret S (2014) Consequences of cancer treatments on adult hippocampal neurogenesis: implications for cognitive function and depressive symptoms. Neuro Oncol 16: 476-92
Green MJ, Myat AM, Emmenegger BA, Wechsler-Reya RJ, Wilson LJ, Wingate RJ (2014) Independently specified Atoh1 domains define novel developmental compartments in rhombomere 1. Development 141: 389-98

2013

Gilthorpe JD, Oozeer F, Nash J, Calvo M, Bennett DL, Lumsden A, Pini A (2013) Extracellular histone H1 is neurotoxic and drives a pro-inflammatory response in microglia. F1000Res 2: 148
Motori E, Puyal J, Toni N, Ghanem A, Angeloni C, Malaguti M, Cantelli-Forti G, Berninger B, Conzelmann KK, Götz M, Winklhofer KF, Hrelia S, Bergami M (2013) Inflammation-induced alteration of astrocyte mitochondrial dynamics requires autophagy for mitochondrial network maintenance. Cell Metab 18: 844-59
Deshpande A, Bergami M, Ghanem A, Conzelmann KK, Lepier A, Götz M, Berninger B (2013) Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb. Proc Natl Acad Sci U S A 110: E1152-61
Ortega F, Gascón S, Masserdotti G, Deshpande A, Simon C, Fischer J, Dimou L, Chichung Lie D, Schroeder T, Berninger B (2013) Oligodendrogliogenic and neurogenic adult subependymal zone neural stem cells constitute distinct lineages and exhibit differential responsiveness to Wnt signalling. Nat Cell Biol 15: 602-13
Sylvester JB, Rich CA, Yi C, Peres JN, Houart C, Streelman JT (2013) Competing signals drive telencephalon diversity. Nat Commun 4: 1745
Basson MA, Wingate RJ (2013) Congenital hypoplasia of the cerebellum: developmental causes and behavioral consequences. Front Neuroanat 7: 29
Wanner SJ, Saeger I, Guthrie S, Prince VE (2013) Facial motor neuron migration advances. Curr Opin Neurobiol 23: 943-50
Clark C, Austen O, Poparic I, Guthrie S (2013) Alpha2-Chimaerin regulates a key axon guidance transition during development of the oculomotor projection. J Neurosci 33: 16540-51
Yap K, Makeyev EV (2013) Regulation of gene expression in mammalian nervous system through alternative pre-mRNA splicing coupled with RNA quality control mechanisms. Mol Cell Neurosci 56: 420-8
Jego S, Glasgow SD, Herrera CG, Ekstrand M, Reed SJ, Boyce R, Friedman J, Burdakov D, Adamantidis AR (2013) Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus. Nat Neurosci 16: 1637-43
Sterratt DC, Lyngholm D, Willshaw DJ, Thompson ID (2013) Standard anatomical and visual space for the mouse retina: computational reconstruction and transformation of flattened retinae with the Retistruct package. PLoS Comput Biol 9: e1002921
Villar-Cerviño V, Molano-Mazón M, Catchpole T, Valdeolmillos M, Henkemeyer M, Martínez LM, Borrell V, Marín O (2013) Contact repulsion controls the dispersion and final distribution of Cajal-Retzius cells. Neuron 77: 457-71
Ciceri G, Dehorter N, Sols I, Huang ZJ, Maravall M, Marín O (2013) Lineage-specific laminar organization of cortical GABAergic interneurons. Nat Neurosci 16: 1199-210
Del Pino I, García-Frigola C, Dehorter N, Brotons-Mas JR, Alvarez-Salvado E, Martínez de Lagrán M, Ciceri G, Gabaldón MV, Moratal D, Dierssen M, Canals S, Marín O, Rico B (2013) Erbb4 deletion from fast-spiking interneurons causes schizophrenia-like phenotypes. Neuron 79: 1152-68

Hay DB, Williams D, Stahl D, Wingate RJ (2013) Using Drawings of the Brain Cell to Exhibit Expertise in Neuroscience: Exploring the Boundaries of Experimental Culture Science Education 93 (3): 468-491
Lleras-Forero L, Tambalo M, Christophorou N, Chambers D, Houart C, Streit A (2013) Neuropeptides: developmental signals in placode progenitor formation. Dev Cell 26: 195-203
Robertshaw E, Matsumoto K, Lumsden A, Kiecker C (2013) Irx3 and Pax6 establish differential competence for Shh-mediated induction of GABAergic and glutamatergic neurons of the thalamus. Proc Natl Acad Sci U S A 110: E3919-26
Antinucci P, Nikolaou N, Meyer MP, Hindges R (2013) Teneurin-3 specifies morphological and functional connectivity of retinal ganglion cells in the vertebrate visual system. Cell Rep 5: 582-92
Levy P, Larsen C (2013) Odd-skipped labels a group of distinct neurons associated with the mushroom body and optic lobe in the adult Drosophila brain. J Comp Neurol 521: 3716-40
Povellato G,Tuxworth RI, Hanger DP,Tear G (2013) Modification of the Drosophila model of in vivo Tau toxicity reveals protective phosphorylation by GSK3β Biology Open Nov 28: bio.201366
van den Brink DM, Banerji O, Tear G (2013) Commissureless regulation of axon outgrowth across the midline is independent of Rab function. PLoS One 8: e64427
Bates TJ, Vonica A, Heasman J, Brivanlou AH, Bell E (2013) Coco regulates dorsoventral specification of germ layers via inhibition of TGF? signalling. Development 140: 4177-4181
Basson MA and Wingate RJ (2013) Congenital hypoplasia of the cerebellum: developmental causes and behavioural consequences.
Hunter PR, Lowe AS, Thompson ID, Meyer MP (2013) Emergent properties of the optic tectum revealed by population analysis of direction and orientation selectivity. J Neurosci 33: 13940-5
Lowe AS, Nikolaou N, Hunter PR, Thompson ID, Meyer MP (2013) A Systems-Based Dissection of Retinal Inputs to the Zebrafish Tectum Reveals Different Rules for Different Functional Classes during Development. J Neurosci 33: 13946-56
Worth DC, Daly CN, Geraldo S, Oozeer F, Gordon-Weeks PR (2013) Drebrin contains a cryptic F-actin-bundling activity regulated by Cdk5 phosphorylation. J Cell Biol 202: 793-806
Thomas-Jinu S, Houart C (2013) Dynamic expression of neurexophilin1 during zebrafish embryonic development. Gene Expr Patterns 13: 395-401
Gilthorpe JD, Oozeer F, Nash J, Calvo M, Bennett DLH, Lumsden A, Pini A (2013) Extracellular histone H1 is neurotoxic and drives a pro-inflammatory response in microglia F1000Research 2:148
Otsuka-Tanaka Y, Oommen S, Kawasaki M, Kawasaki K, Imam N, Jalani-Ghazani F, Hindges R, Sharpe PT, Ohazama A (2013) Oral lining mucosa development depends on mesenchymal microRNAs. J Dent Res 92: 229-34
Maiorano NA, Hindges R (2013) Restricted perinatal retinal degeneration induces retina reshaping and correlated structural rearrangement of the retinotopic map. Nat Commun 4: 1938
Sousa-Nunes R, Somers WG (2013) Mechanisms of asymmetric progenitor divisions in the Drosophila central nervous system. Adv Exp Med Biol 786: 79-102