Publications

2001

Tio M, Udolph G, Yang X, Chia W (2001) cdc2 links the Drosophila cell cycle and asymmetric division machineries. Nature 409: 1063-7
Udolph G, Rath P, Chia W (2001) A requirement for Notch in the genesis of a subset of glial cells in the Drosophila embryonic central nervous system which arise through asymmetric divisions. Development 128: 1457-66
Morin X, Daneman R, Zavortink M, Chia W (2001) A protein trap strategy to detect GFP-tagged proteins expressed from their endogenous loci in Drosophila. Proc Natl Acad Sci U S A 98: 15050-5
Altmann CR, Bell E, Sczyrba A, Pun J, Bekiranov S, Gaasterland T, Brivanlou AH (2001) Microarray-based analysis of early development in Xenopus laevis. Dev Biol 236: 64-75
Simeone A, Acampora D (2001) The role of Otx2 in organizing the anterior patterning in mouse. Int J Dev Biol 45: 337-45

2000

Schinder AF, Berninger B, Poo M (2000) Postsynaptic target specificity of neurotrophin-induced presynaptic potentiation. Neuron 25: 151-63
Grammatopoulos GA, Bell E, Toole L, Lumsden A, Tucker AS (2000) Homeotic transformation of branchial arch identity after Hoxa2 overexpression. Development 127: 5355-65
Alves PM, Nunes R, Zhang C, Maycock CD, Sonnewald U, Carrondo MJ, Santos H (2000) Metabolism of 3-(13)C-malate in primary cultures of mouse astrocytes. Dev Neurosci 22: 456-62
Pazman C, Mayes CA, Fanto M, Haynes SR, Mlodzik M (2000) Rasputin, the Drosophila homologue of the RasGAP SH3 binding protein, functions in ras- and Rho-mediated signaling. Development 127: 1715-25
Fanto M, Weber U, Strutt DI, Mlodzik M (2000) Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye. Curr Biol 10: 979-88
Roversi P, Blanc E, Vonrhein C, Evans G, Bricogne G (2000) Modelling prior distributions of atoms for macromolecular refinement and completion. Acta Crystallogr D Biol Crystallogr 56: 1316-23
Blanc E, Restori R, Schwarzenbach D, Burgi HB, Fortsch M, Venugopalan P, Ermer O (2000) Orientational disorder as a function of temperature in the clathrate structure of hydroquinone and C60 Acta Crystallogr B 56 (Pt 6): 1003-10
Stienstra CM, van Diepen MT, Joëls M (2000) Field responses to perforant path stimulation in the rat dentate gyrus: role of corticosterone and NMDA-receptor activation. Brain Res 854: 230-4
Roth S, Johansson M, Loukola A, Peltomäki P, Järvinen H, Mecklin JP, Aaltonen LA (2000) Mutation analysis of SMAD2, SMAD3, and SMAD4 genes in hereditary non-polyposis colorectal. J Med Genet 37: 298-300
Prinjha R, Moore SE, Vinson M, Blake S, Morrow R, Christie G, Michalovich D, Simmons DL, Walsh FS (2000) Inhibitor of neurite outgrowth in humans. Nature 403: 383-4
Harrison DC, Roberts J, Campbell CA, Crook B, Davis R, Deen K, Meakin J, Michalovich D, Price J, Stammers M, Maycox PR (2000) TR3 death receptor expression in the normal and ischaemic brain. Neuroscience 96: 147-60
Robbins MJ, Michalovich D, Hill J, Calver AR, Medhurst AD, Gloger I, Sims M, Middlemiss DN, Pangalos MN (2000) Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C). Genomics 67: 8-18
Ozaki K, Kikly K, Michalovich D, Young PR, Leonard WJ (2000) Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain. Proc Natl Acad Sci U S A 97: 11439-44
Kiecker C, Müller F, Wu W, Glinka A, Strähle U, Niehrs C (2000) Phenotypic effects in Xenopus and zebrafish suggest that one-eyed pinhead functions as antagonist of BMP signalling. Mech Dev 94: 37-46
Burrone J, Lagnado L (2000) Synaptic depression and the kinetics of exocytosis in retinal bipolar cells. J Neurosci 20: 568-78
Williams DW, Tyrer M, Shepherd D (2000) Tau and tau reporters disrupt central projections of sensory neurons in Drosophila. J Comp Neurol 428: 630-40
Drescher U (2000) Eph receptor tyrosine kinases and their ligands in development. Ernst Schering Res Found Workshop : 151-64
Drescher U (2000) Excitation at the synapse: Eph receptors team up with NMDA receptors. Cell 103: 1005-8
Hart AW, Baeza N, Apelqvist A, Edlund H (2000) Attenuation of FGF signalling in mouse beta-cells leads to diabetes. Nature 408: 864-8
Basson MA, Zamoyska R (2000) The CD4/CD8 lineage decision: integration of signalling pathways. Immunol Today 21: 509-14
Basson MA, Wilson TJ, Legname GA, Sarner N, Tomlinson PD, Tybulewicz VL, Zamoyska R (2000) Early growth response (Egr)-1 gene induction in the thymus in response to TCR ligation during early steps in positive selection is not required for CD8 lineage commitment. J Immunol 165: 2444-50
Basson MA, Zamoyska R (2000) Insights into T-cell development from studies using transgenic and knockout mice. Methods Mol Biol 134: 3-22
Buchner G, Orfanelli U, Quaderi N, Bassi MT, Andolfi G, Ballabio A, Franco B (2000) Identification of a new EGF-repeat-containing gene from human Xp22: a candidate for developmental disorders. Genomics 65: 16-23
Medhurst AWD, Chambers D, Gray J, Davis JB, Shale JA, Mason I, Jenner P, and Newton RA (2000) Practical aspects of the experimental design for differential display of transcripts obtained from complex tissues. In “Differential Display. A Practical Approach” Eds. R.A. Leslie and H.A.Robertson. OUP, Oxford, UK. : 35-66
Formstone CJ, Barclay J, Rees M, Little PF (2000) Chromosomal localization of Celsr2 and Celsr3 in the mouse; Celsr3 is a candidate for the tippy (tip) lethal mutant on chromosome 9. Mamm Genome 11: 392-4
Mason I (2000) The RET receptor tyrosine kinase: activation, signalling and significance in neural development and disease. Pharm Acta Helv 74: 261-4
Prinjha RK, Shapland CE, Hsuan JJ, Totty NF, Mason IJ, Lawson D (2000) Cloning and sequencing of cDNAs encoding the actin cross-linking protein transgelin defines a new family of actin-associated proteins. Cell Motil Cytoskeleton 28: 243-55
Cardoso WV, Itoh A, Nogawa H, Mason I, Brody JS (2000) FGF-1 and FGF-7 induce distinct patterns of growth and differentiation in embryonic lung epithelium. Dev Dyn 208: 398-405
Ledig MM, McKinnell IW, Mrsic-Flogel T, Wang J, Alvares C, Mason I, Bixby JL, Mueller BK, Stoker AW (2000) Expression of receptor tyrosine phosphatases during development of the retinotectal projection of the chick. J Neurobiol 39: 81-96
Walshe J, Mason I (2000) Expression of FGFR1, FGFR2 and FGFR3 during early neural development in the chick embryo. Mech Dev 90: 103-10
Chambers D, Medhurst AD, Walsh FS, Price J, Mason I (2000) Differential display of genes expressed at the midbrain - hindbrain junction identifies sprouty2: an FGF8-inducible member of a family of intracellular FGF antagonists. Mol Cell Neurosci 15: 22-35
Irving C, Mason I (2000) Signalling by FGF8 from the isthmus patterns anterior hindbrain and establishes the anterior limit of Hox gene expression. Development 127: 177-86
Chambers D, Mason I (2000) Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling. Mech Dev 91: 361-4
Ernsberger U, Reissmann E, Mason I, Rohrer H (2000) The expression of dopamine beta-hydroxylase, tyrosine hydroxylase, and Phox2 transcription factors in sympathetic neurons: evidence for common regulation during noradrenergic induction and diverging regulation later in development. Mech Dev 92: 169-77
Beer HD, Vindevoghel L, Gait MJ, Revest JM, Duan DR, Mason I, Dickson C, Werner S (2000) Fibroblast growth factor (FGF) receptor 1-IIIb is a naturally occurring functional receptor for FGFs that is preferentially expressed in the skin and the brain. J Biol Chem 275: 16091-7
Mackenzie S, Walsh FS, Graham A (2000) Migration of hypoglossal myoblast precursors. Dev Dyn 213: 349-58
Boyd JD, Casagrande VA (2000) Relationships between cytochrome oxidase (CO) blobs in primate primary visual cortex (V1) and the distribution of neurons projecting to the middle temporal area (MT). J Comp Neurol 409: 573-91
Graham A (2000) Animal phylogeny: root and branch surgery. Curr Biol 10: R36-8
Graham A (2000) Mammalian development: new trick for an old dog. Curr Biol 10: R401-3
Graham A, Begbie J (2000) Neurogenic placodes: a common front. Trends Neurosci 23: 313-6
Veitch E, Begbie J, Schilling TF, Smith MM, Graham A (2000) Pharyngeal arch patterning in the absence of neural crest. Curr Biol 9: 1481-4
Basson MA, Bommhardt U, Cole MS, Tso JY, Zamoyska R (2000) CD3 ligation on immature thymocytes generates antagonist-like signals appropriate for CD8 lineage commitment, independently of T cell receptor specificity. J Exp Med 187: 1249-60
Huai J, Drescher U (2000) An ephrin-A-dependent signaling pathway controls integrin function and is linked to the tyrosine phosphorylation of a 120-kDa protein. J Biol Chem 276: 6689-94

1999

Ming G, Song H, Berninger B, Inagaki N, Tessier-Lavigne M, Poo M (1999) Phospholipase C-gamma and phosphoinositide 3-kinase mediate cytoplasmic signaling in nerve growth cone guidance. Neuron 23: 139-48
Berninger B, Schinder AF, Poo MM (1999) Synaptic reliability correlates with reduced susceptibility to synaptic potentiation by brain-derived neurotrophic factor. Learn Mem 6: 232-42
Meyer MP, Clarke JD, Patel K, Townsend-Nicholson A, Burnstock G (1999) Selective expression of purinoceptor cP2Y1 suggests a role for nucleotide signalling in development of the chick embryo. Dev Dyn 214: 152-8
Meyer MP, Gröschel-Stewart U, Robson T, Burnstock G (1999) Expression of two ATP-gated ion channels, P2X5 and P2X6, in developing chick skeletal muscle. Dev Dyn 216: 442-9
Jungbluth S, Bell E, Lumsden A (1999) Specification of distinct motor neuron identities by the singular activities of individual Hox genes. Development 126: 2751-8
Bell E, Lumsden A, Graham A (1999) Expression of GATA-2 in the developing avian rhombencephalon. Mech Dev 84: 173-6
Bell E, Wingate RJ, Lumsden A (1999) Homeotic transformation of rhombomere identity after localized Hoxb1 misexpression. Science 284: 2168-71
Wingate RJ (1999) Microscopy and photomicrography techniques. Methods Mol Biol 97: 711-33
Millen KJ, Millonig JH, Wingate RJ, Alder J, Hatten ME (1999) Neurogenetics of the cerebellar system. J Child Neurol 14: 574-81; discussion 581-2
Wingate RJ, Hatten ME (1999) The role of the rhombic lip in avian cerebellum development. Development 126: 4395-404
Chalmers RM, Andreae L, Wood NW, Durai Raj RV, Casey AT (1999) Familial hydrocephalus. J Neurol Neurosurg Psychiatry 67: 410-11
Fanto M, Mlodzik M (1999) Asymmetric Notch activation specifies photoreceptors R3 and R4 and planar polarity in the Drosophila eye. Nature 397: 523-6
Lieberam I, Förster I (1999) The murine beta-chemokine TARC is expressed by subsets of dendritic cells and attracts primed CD4+ T cells. Eur J Immunol 29: 2684-94
Lowe A, Finch A, Boniface D, Chaudhuri R, Shekhdar J (1999) Diagnostic image quality of mobile neonatal chest X-rays and the radiation exposure incurred. Br J Radiol 72: 55-61
Zhou G, Somasundaram T, Blanc E, Chen Z, Chapman MS (1999) Critical initial real-space refinement in the structure determination of arginine kinase. Acta Crystallogr D Biol Crystallogr 55: 835-45
Chen Z, Blanc E, Chapman MS (1999) Real-space molecular-dynamics structure refinement. Acta Crystallogr D Biol Crystallogr 55: 464-8
Chen Z, Blanc E, Chapman MS (1999) Improved free R factors for cross-validation of macromolecular structure - importance for real-space refinement. Acta Crystallogr D Biol Crystallogr 55: 219-24
Herman MA, Ch'ng Q, Hettenbach SM, Ratliff TM, Kenyon C, Herman RK (1999) EGL-27 is similar to a metastasis-associated factor and controls cell polarity and cell migration in C. elegans. Development 126: 1055-64
Ch'ng Q, Kenyon C (1999) egl-27 generates anteroposterior patterns of cell fusion in C. elegans by regulating Hox gene expression and Hox protein function. Development 126: 3303-12
Ylikorkala A, Avizienyte E, Tomlinson IP, Tiainen M, Roth S, Loukola A, Hemminki A, Johansson M, Sistonen P, Markie D, Neale K, Phillips R, Zauber P, Twama T, Sampson J, Järvinen H, Mäkelä TP, Aaltonen LA (1999) Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer. Hum Mol Genet 8: 45-51
Bertuzzi S, Hindges R, Mui SH, O'Leary DD, Lemke G (1999) The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain. Genes Dev 13: 3092-105
Gomis A, Burrone J, Lagnado L (1999) Two actions of calcium regulate the supply of releasable vesicles at the ribbon synapse of retinal bipolar cells. J Neurosci 19: 6309-17
Williams DW, Shepherd D (1999) Persistent larval sensory neurons in adult Drosophila melanogaster. J Neurobiol 39: 275-86
Dütting D, Handwerker C, Drescher U (1999) Topographic targeting and pathfinding errors of retinal axons following overexpression of ephrinA ligands on retinal ganglion cell axons. Dev Biol 216: 297-311
Hornberger MR, Dütting D, Ciossek T, Yamada T, Handwerker C, Lang S, Weth F, Huf J, Wessel R, Logan C, Tanaka H, Drescher U (1999) Modulation of EphA receptor function by coexpressed ephrinA ligands on retinal ganglion cell axons. Neuron 22: 731-42
Apelqvist A, Li H, Sommer L, Beatus P, Anderson DJ, Honjo T, Hrabe de Angelis M, Lendahl U, Edlund H (1999) Notch signalling controls pancreatic cell differentiation. Nature 400: 877-81
Mee PJ, Turner M, Basson MA, Costello PS, Zamoyska R, Tybulewicz VL (1999) Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase-deficient mice. Eur J Immunol 29: 2923-33
Bommhardt U, Basson MA, Krummrei U, Zamoyska R (1999) Activation of the extracellular signal-related kinase/mitogen-activated protein kinase pathway discriminates CD4 versus CD8 lineage commitment in the thymus. J Immunol 163: 715-22
Buchner G, Montini E, Andolfi G, Quaderi N, Cainarca S, Messali S, Bassi MT, Ballabio A, Meroni G, Franco B (1999) MID2, a homologue of the Opitz syndrome gene MID1: similarities in subcellular localization and differences in expression during development. Hum Mol Genet 8: 1397-407
Bulfone A, Martinez S, Marigo V, Campanella M, Basile A, Quaderi N, Gattuso C, Rubenstein JL, Ballabio A (1999) Expression pattern of the Tbr2 (Eomesodermin) gene during mouse and chick brain development. Mech Dev 84: 133-8