Publications

2001

Acampora D, Gulisano M, Broccoli V, Simeone A (2001) Otx genes in brain morphogenesis. Prog Neurobiol 64: 69-95
Hughes SM (2001) Muscle development: reversal of the differentiated state. Curr Biol 11: R237-9
Hampson R, Hughes SM (2001) Muscular expressions: profiling genes in complex tissues. Genome Biol 2: REVIEWS1033
Guthrie S (2001) Axon guidance: Robos make the rules. Curr Biol 11: R300-3
Jacob J, Hacker A, Guthrie S (2001) Mechanisms and molecules in motor neuron specification and axon pathfinding. Bioessays 23: 582-95
Kinrade EF, Brates T, Tear G, Hidalgo A (2001) Roundabout signalling, cell contact and trophic support confine longitudinal glia and axons in the Drosophila CNS. Development 128: 207-16
Fritzsch B, Signore M, Simeone A, Fritzsch B (2001) Otx1 null mutant mice show partial segregation of sensory epithelia comparable to lamprey ears. Dev Genes Evol 211: 388-96
Acampora D, Boyl PP, Martinez-Barbera JP, Annino A, Signore M, Simeone A (2001) Otx genes in evolution: are they involved in instructing the vertebrate brain morphology? J Anat 199: 53-62
Boyl PP, Signore M, Annino A, Barbera JP, Acampora D, Simeone A (2001) Otx genes in the development and evolution of the vertebrate brain. Int J Dev Neurosci 19: 353-63
Martinez-Morales JR, Signore M, Acampora D, Simeone A, Bovolenta P (2001) Otx genes are required for tissue specification in the developing eye. Development 128: 2019-30
Rashid T, Banerjee M, Nikolic M (2001) Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology. J Biol Chem 276: 49043-52
Schneider RA, Hu D, Rubenstein JL, Maden M, Helms JA (2001) Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining FGF8 and SHH. Development 128: 2755-67
Schmidt C, Christ B, Maden M, Brand-Saberi B, Patel K (2001) Regulation of Epha4 expression in paraxial and lateral plate mesoderm by ectoderm-derived signals. Dev Dyn 220: 377-86
Bell E, Ensini M, Gulisano M, Lumsden A (2001) Dynamic domains of gene expression in the early avian forebrain. Dev Biol 236: 76-88
Dupé V, Lumsden A (2001) Hindbrain patterning involves graded responses to retinoic acid signalling. Development 128: 2199-208
Zeltser LM, Larsen CW, Lumsden A (2001) A new developmental compartment in the forebrain regulated by Lunatic fringe. Nat Neurosci 4: 683-4
Larsen CW, Zeltser LM, Lumsden A (2001) Boundary formation and compartition in the avian diencephalon. J Neurosci 21: 4699-711
Jungbluth S, Larsen C, Wizenmann A, Lumsden A (2001) Cell mixing between the embryonic midbrain and hindbrain. Curr Biol 11: 204-7
Schubert FR, Dietrich S, Mootoosamy RC, Chapman SC, Lumsden A (2001) Lbx1 marks a subset of interneurons in chick hindbrain and spinal cord. Mech Dev 101: 181-5
Chapman SC, Collignon J, Schoenwolf GC, Lumsden A (2001) Improved method for chick whole-embryo culture using a filter paper carrier. Dev Dyn 220: 284-9
Jungbluth S, Phelps C, Lumsden A (2001) CEPU-1 expression in the early embryonic chick brain. Mech Dev 101: 195-7
Lluís F, Roma J, Suelves M, Parra M, Aniorte G, Gallardo E, Illa I, Rodríguez L, Hughes SM, Carmeliet P, Roig M, Muñoz-Cánoves P (2001) Urokinase-dependent plasminogen activation is required for efficient skeletal muscle regeneration in vivo. Blood 97: 1703-11
Coutelle O, Blagden CS, Hampson R, Halai C, Rigby PW, Hughes SM (2001) Hedgehog signalling is required for maintenance of myf5 and myoD expression and timely terminal differentiation in zebrafish adaxial myogenesis. Dev Biol 236: 136-50
Heisenberg CP, Houart C, Take-Uchi M, Rauch GJ, Young N, Coutinho P, Masai I, Caneparo L, Concha ML, Geisler R, Dale TC, Wilson SW, Stemple DL (2001) A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon. Genes Dev 15: 1427-34
Barrett C, Guthrie S (2001) Expression patterns of the netrin receptor UNC5H1 among developing motor neurons in the embryonic rat hindbrain. Mech Dev 106: 163-6
Gavalas A, Trainor P, Ariza-McNaughton L, Krumlauf R (2001) Synergy between Hoxa1 and Hoxb1: the relationship between arch patterning and the generation of cranial neural crest. Development 128: 3017-27
Di Rocco G, Gavalas A, Popperl H, Krumlauf R, Mavilio F, Zappavigna V (2001) The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function. J Biol Chem 276: 20506-15
Yamada T, Okafuji T, Ohta K, Handwerker C, Drescher U, Tanaka H (2001) Analysis of ephrin-A2 in the chick retinotectal projection using a function-blocking monoclonal antibody. J Neurobiol 47: 245-54
Knöll B, Zarbalis K, Wurst W, Drescher U (2001) A role for the EphA family in the topographic targeting of vomeronasal axons. Development 128: 895-906
Knöll B, Isenmann S, Kilic E, Walkenhorst J, Engel S, Wehinger J, Bähr M, Drescher U (2001) Graded expression patterns of ephrin-As in the superior colliculus after lesion of the adult mouse optic nerve. Mech Dev 106: 119-27
Dunican DJ, Williams EJ, Howell FV, Doherty P (2001) Selective inhibition of fibroblast growth factor (FGF)-stimulated mitogenesis by a FGF receptor-1-derived phosphopeptide. Cell Growth Differ 12: 255-64
Dunican DJ, Doherty P (2001) Designing cell-permeant phosphopeptides to modulate intracellular signaling pathways. Biopolymers 60: 45-60
Williams G, Williams EJ, Doherty P (2001) Dimeric versions of two short N-cadherin binding motifs (HAVDI and INPISG) function as N-cadherin agonists. J Biol Chem 277: 4361-7
Williams EJ, Williams G, Howell FV, Skaper SD, Walsh FS, Doherty P (2001) Identification of an N-cadherin motif that can interact with the fibroblast growth factor receptor and is required for axonal growth. J Biol Chem 276: 43879-86
Utton MA, Eickholt B, Howell FV, Wallis J, Doherty P (2001) Soluble N-cadherin stimulates fibroblast growth factor receptor dependent neurite outgrowth and N-cadherin and the fibroblast growth factor receptor co-cluster in cells. J Neurochem 76: 1421-30
Cafferty WB, Gardiner NJ, Gavazzi I, Powell J, McMahon SB, Heath JK, Munson J, Cohen J, Thompson SW (2001) Leukemia inhibitory factor determines the growth status of injured adult sensory neurons. J Neurosci 21: 7161-70
Bahri SM, Chia W, Yang X (2001) Characterization and mutant analysis of the Drosophila sema 5c gene. Dev Dyn 221: 322-30
Cai Y, Chia W, Yang X (2001) A family of snail-related zinc finger proteins regulates two distinct and parallel mechanisms that mediate Drosophila neuroblast asymmetric divisions. EMBO J 20: 1704-14
Bahri SM, Chia W, Yang X (2001) The Drosophila homolog of human AF10/AF17 leukemia fusion genes (Dalf) encodes a zinc finger/leucine zipper nuclear protein required in the nervous system for maintaining EVE expression and normal growth. Mech Dev 100: 291-301
Helps NR, Cohen PT, Bahri SM, Chia W, Babu K (2001) Interaction with protein phosphatase 1 Is essential for bifocal function during the morphogenesis of the Drosophila compound eye. Mol Cell Biol 21: 2154-64
Tio M, Udolph G, Yang X, Chia W (2001) cdc2 links the Drosophila cell cycle and asymmetric division machineries. Nature 409: 1063-7
Udolph G, Rath P, Chia W (2001) A requirement for Notch in the genesis of a subset of glial cells in the Drosophila embryonic central nervous system which arise through asymmetric divisions. Development 128: 1457-66
Morin X, Daneman R, Zavortink M, Chia W (2001) A protein trap strategy to detect GFP-tagged proteins expressed from their endogenous loci in Drosophila. Proc Natl Acad Sci U S A 98: 15050-5
Altmann CR, Bell E, Sczyrba A, Pun J, Bekiranov S, Gaasterland T, Brivanlou AH (2001) Microarray-based analysis of early development in Xenopus laevis. Dev Biol 236: 64-75
Simeone A, Acampora D (2001) The role of Otx2 in organizing the anterior patterning in mouse. Int J Dev Biol 45: 337-45

2000

Schinder AF, Berninger B, Poo M (2000) Postsynaptic target specificity of neurotrophin-induced presynaptic potentiation. Neuron 25: 151-63
Grammatopoulos GA, Bell E, Toole L, Lumsden A, Tucker AS (2000) Homeotic transformation of branchial arch identity after Hoxa2 overexpression. Development 127: 5355-65
Alves PM, Nunes R, Zhang C, Maycock CD, Sonnewald U, Carrondo MJ, Santos H (2000) Metabolism of 3-(13)C-malate in primary cultures of mouse astrocytes. Dev Neurosci 22: 456-62
Pazman C, Mayes CA, Fanto M, Haynes SR, Mlodzik M (2000) Rasputin, the Drosophila homologue of the RasGAP SH3 binding protein, functions in ras- and Rho-mediated signaling. Development 127: 1715-25
Fanto M, Weber U, Strutt DI, Mlodzik M (2000) Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye. Curr Biol 10: 979-88
Roversi P, Blanc E, Vonrhein C, Evans G, Bricogne G (2000) Modelling prior distributions of atoms for macromolecular refinement and completion. Acta Crystallogr D Biol Crystallogr 56: 1316-23
Blanc E, Restori R, Schwarzenbach D, Burgi HB, Fortsch M, Venugopalan P, Ermer O (2000) Orientational disorder as a function of temperature in the clathrate structure of hydroquinone and C60 Acta Crystallogr B 56 (Pt 6): 1003-10
Stienstra CM, van Diepen MT, Joëls M (2000) Field responses to perforant path stimulation in the rat dentate gyrus: role of corticosterone and NMDA-receptor activation. Brain Res 854: 230-4
Roth S, Johansson M, Loukola A, Peltomäki P, Järvinen H, Mecklin JP, Aaltonen LA (2000) Mutation analysis of SMAD2, SMAD3, and SMAD4 genes in hereditary non-polyposis colorectal. J Med Genet 37: 298-300
Prinjha R, Moore SE, Vinson M, Blake S, Morrow R, Christie G, Michalovich D, Simmons DL, Walsh FS (2000) Inhibitor of neurite outgrowth in humans. Nature 403: 383-4
Harrison DC, Roberts J, Campbell CA, Crook B, Davis R, Deen K, Meakin J, Michalovich D, Price J, Stammers M, Maycox PR (2000) TR3 death receptor expression in the normal and ischaemic brain. Neuroscience 96: 147-60
Robbins MJ, Michalovich D, Hill J, Calver AR, Medhurst AD, Gloger I, Sims M, Middlemiss DN, Pangalos MN (2000) Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C). Genomics 67: 8-18
Ozaki K, Kikly K, Michalovich D, Young PR, Leonard WJ (2000) Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain. Proc Natl Acad Sci U S A 97: 11439-44
Kiecker C, Müller F, Wu W, Glinka A, Strähle U, Niehrs C (2000) Phenotypic effects in Xenopus and zebrafish suggest that one-eyed pinhead functions as antagonist of BMP signalling. Mech Dev 94: 37-46
Burrone J, Lagnado L (2000) Synaptic depression and the kinetics of exocytosis in retinal bipolar cells. J Neurosci 20: 568-78
Williams DW, Tyrer M, Shepherd D (2000) Tau and tau reporters disrupt central projections of sensory neurons in Drosophila. J Comp Neurol 428: 630-40
Drescher U (2000) Eph receptor tyrosine kinases and their ligands in development. Ernst Schering Res Found Workshop : 151-64
Drescher U (2000) Excitation at the synapse: Eph receptors team up with NMDA receptors. Cell 103: 1005-8
Hart AW, Baeza N, Apelqvist A, Edlund H (2000) Attenuation of FGF signalling in mouse beta-cells leads to diabetes. Nature 408: 864-8
Basson MA, Zamoyska R (2000) The CD4/CD8 lineage decision: integration of signalling pathways. Immunol Today 21: 509-14
Basson MA, Wilson TJ, Legname GA, Sarner N, Tomlinson PD, Tybulewicz VL, Zamoyska R (2000) Early growth response (Egr)-1 gene induction in the thymus in response to TCR ligation during early steps in positive selection is not required for CD8 lineage commitment. J Immunol 165: 2444-50
Basson MA, Zamoyska R (2000) Insights into T-cell development from studies using transgenic and knockout mice. Methods Mol Biol 134: 3-22
Buchner G, Orfanelli U, Quaderi N, Bassi MT, Andolfi G, Ballabio A, Franco B (2000) Identification of a new EGF-repeat-containing gene from human Xp22: a candidate for developmental disorders. Genomics 65: 16-23
Medhurst AWD, Chambers D, Gray J, Davis JB, Shale JA, Mason I, Jenner P, and Newton RA (2000) Practical aspects of the experimental design for differential display of transcripts obtained from complex tissues. In “Differential Display. A Practical Approach” Eds. R.A. Leslie and H.A.Robertson. OUP, Oxford, UK. : 35-66
Formstone CJ, Barclay J, Rees M, Little PF (2000) Chromosomal localization of Celsr2 and Celsr3 in the mouse; Celsr3 is a candidate for the tippy (tip) lethal mutant on chromosome 9. Mamm Genome 11: 392-4
Mason I (2000) The RET receptor tyrosine kinase: activation, signalling and significance in neural development and disease. Pharm Acta Helv 74: 261-4
Prinjha RK, Shapland CE, Hsuan JJ, Totty NF, Mason IJ, Lawson D (2000) Cloning and sequencing of cDNAs encoding the actin cross-linking protein transgelin defines a new family of actin-associated proteins. Cell Motil Cytoskeleton 28: 243-55
Cardoso WV, Itoh A, Nogawa H, Mason I, Brody JS (2000) FGF-1 and FGF-7 induce distinct patterns of growth and differentiation in embryonic lung epithelium. Dev Dyn 208: 398-405
Ledig MM, McKinnell IW, Mrsic-Flogel T, Wang J, Alvares C, Mason I, Bixby JL, Mueller BK, Stoker AW (2000) Expression of receptor tyrosine phosphatases during development of the retinotectal projection of the chick. J Neurobiol 39: 81-96
Walshe J, Mason I (2000) Expression of FGFR1, FGFR2 and FGFR3 during early neural development in the chick embryo. Mech Dev 90: 103-10
Chambers D, Medhurst AD, Walsh FS, Price J, Mason I (2000) Differential display of genes expressed at the midbrain - hindbrain junction identifies sprouty2: an FGF8-inducible member of a family of intracellular FGF antagonists. Mol Cell Neurosci 15: 22-35
Irving C, Mason I (2000) Signalling by FGF8 from the isthmus patterns anterior hindbrain and establishes the anterior limit of Hox gene expression. Development 127: 177-86
Chambers D, Mason I (2000) Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling. Mech Dev 91: 361-4
Ernsberger U, Reissmann E, Mason I, Rohrer H (2000) The expression of dopamine beta-hydroxylase, tyrosine hydroxylase, and Phox2 transcription factors in sympathetic neurons: evidence for common regulation during noradrenergic induction and diverging regulation later in development. Mech Dev 92: 169-77