Publications

2001

Meyer MP, Swann K, Burnstock G, Clarke JD (2001) The extracellular ATP receptor, cP2Y(1), inhibits cartilage formation in micromass cultures of chick limb mesenchyme. Dev Dyn 222: 494-505
Harsum S, Clarke JD, Martin P (2001) A reciprocal relationship between cutaneous nerves and repairing skin wounds in the developing chick embryo. Dev Biol 238: 27-39
Chen LF, Blanc E, Chapman MS, Taylor KA (2001) Real space refinement of acto-myosin structures from sectioned muscle. J Struct Biol 133: 221-32
Retailleau P, Yin Y, Hu M, Roach J, Bricogne G, Vonrhein C, Roversi P, Blanc E, Sweet RM, Carter CW (2001) High-resolution experimental phases for tryptophanyl-tRNA synthetase (TrpRS) complexed with tryptophanyl-5'AMP. Acta Crystallogr D Biol Crystallogr 57: 1595-608
Lehto M, Laitinen S, Chinetti G, Johansson M, Ehnholm C, Staels B, Ikonen E, Olkkonen VM (2001) The OSBP-related protein family in humans. J Lipid Res 42: 1203-13
Zhu Y, Michalovich D, Wu H, Tan KB, Dytko GM, Mannan IJ, Boyce R, Alston J, Tierney LA, Li X, Herrity NC, Vawter L, Sarau HM, Ames RS, Davenport CM, Hieble JP, Wilson S, Bergsma DJ, Fitzgerald LR (2001) Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Mol Pharmacol 59: 434-41
Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CG, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harri (2001) AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1. J Biol Chem 276: 28969-75
Kiecker C, Niehrs C (2001) The role of prechordal mesendoderm in neural patterning. Curr Opin Neurobiol 11: 27-33
Kiecker C, Niehrs C (2001) A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus. Development 128: 4189-201
Scholpp S, Brand M (2001) Morpholino-induced knockdown of zebrafish engrailed genes eng2 and eng3 reveals redundant and unique functions in midbrain--hindbrain boundary development. Genesis 30: 129-33
Eickholt BJ, Graham A, Lumsden A, Wizenmann A (2001) Rhombomere interactions control the segmental differentiation of hindbrain neurons. Mol Cell Neurosci 18: 141-8
Krug K, Akerman CJ, Thompson ID (2001) Responses of neurons in neonatal cortex and thalamus to patterned visual stimulation through the naturally closed lids. J Neurophysiol 85: 1436-43
Burrone J, Murthy VN (2001) Synaptic plasticity: rush hour traffic in the AMPA lanes. Curr Biol 11: R274-7
Leibowitz G, Melloul D, Yuli M, Gross DJ, Apelqvist A, Edlund H, Cerasi E, Kaiser N (2001) Defective glucose-regulated insulin gene expression associated with PDX-1 deficiency in the Psammomys obesus model of type 2 diabetes. Diabetes 50 Suppl 1: S138-9
Leibowitz G, Ferber S, Apelqvist A Edlund H, Gross DJ, Cerasi E, Melloul D, Kaiser N (2001) IPF1/PDX1 deficiency and beta-cell dysfunction in Psammomys obesus, an animal With type 2 diabetes. Diabetes 50: 1799-806
Basson MA, Zamoyska R (2001) Insights into T-cell development from studies using transgenic and knockout mice. Mol Biotechnol 18: 11-23
Mason I, Chambers D, Shamim H, Walshe J, Irving C (2001) Regulation and function of FGF8 in patterning of midbrain and anterior hindbrain. Biochem Cell Biol 78: 577-84
Gustafson AL, Mason I (2001) Expression of receptor tyrosine phosphatase gamma during early development of the chick embryo. Mech Dev 98: 183-6
Reifers F, Adams J, Mason IJ, Schulte-Merker S, Brand M (2001) Overlapping and distinct functions provided by fgf17, a new zebrafish member of the Fgf8/17/18 subgroup of Fgfs. Mech Dev 99: 39-49
Graham A (2001) The evolution of the vertebrates--genes and development. Curr Opin Genet Dev 10: 624-8
Graham A, Smith A (2001) Patterning the pharyngeal arches. Bioessays 23: 54-61
Graham A (2001) The development and evolution of the pharyngeal arches. J Anat 199: 133-41
Graham A (2001) Development. Hear, hear, for the inner ear. Science 290: 1904-5
Smith A, Graham A (2001) Restricting Bmp-4 mediated apoptosis in hindbrain neural crest. Dev Dyn 220: 276-83
McGonnell IM, McKay IJ, Graham A (2001) A population of caudally migrating cranial neural crest cells: functional and evolutionary implications. Dev Biol 236: 354-63
Wingate RJ (2001) The rhombic lip and early cerebellar development. Curr Opin Neurobiol 11: 82-8
Tear G (2001) A new code for axons. Nature 409: 472-3
Acampora D, Gulisano M, Broccoli V, Simeone A (2001) Otx genes in brain morphogenesis. Prog Neurobiol 64: 69-95
Hughes SM (2001) Muscle development: reversal of the differentiated state. Curr Biol 11: R237-9
Hampson R, Hughes SM (2001) Muscular expressions: profiling genes in complex tissues. Genome Biol 2: REVIEWS1033
Guthrie S (2001) Axon guidance: Robos make the rules. Curr Biol 11: R300-3
Jacob J, Hacker A, Guthrie S (2001) Mechanisms and molecules in motor neuron specification and axon pathfinding. Bioessays 23: 582-95
Kinrade EF, Brates T, Tear G, Hidalgo A (2001) Roundabout signalling, cell contact and trophic support confine longitudinal glia and axons in the Drosophila CNS. Development 128: 207-16
Fritzsch B, Signore M, Simeone A, Fritzsch B (2001) Otx1 null mutant mice show partial segregation of sensory epithelia comparable to lamprey ears. Dev Genes Evol 211: 388-96
Acampora D, Boyl PP, Martinez-Barbera JP, Annino A, Signore M, Simeone A (2001) Otx genes in evolution: are they involved in instructing the vertebrate brain morphology? J Anat 199: 53-62
Boyl PP, Signore M, Annino A, Barbera JP, Acampora D, Simeone A (2001) Otx genes in the development and evolution of the vertebrate brain. Int J Dev Neurosci 19: 353-63
Martinez-Morales JR, Signore M, Acampora D, Simeone A, Bovolenta P (2001) Otx genes are required for tissue specification in the developing eye. Development 128: 2019-30
Rashid T, Banerjee M, Nikolic M (2001) Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology. J Biol Chem 276: 49043-52
Schneider RA, Hu D, Rubenstein JL, Maden M, Helms JA (2001) Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining FGF8 and SHH. Development 128: 2755-67
Schmidt C, Christ B, Maden M, Brand-Saberi B, Patel K (2001) Regulation of Epha4 expression in paraxial and lateral plate mesoderm by ectoderm-derived signals. Dev Dyn 220: 377-86
Bell E, Ensini M, Gulisano M, Lumsden A (2001) Dynamic domains of gene expression in the early avian forebrain. Dev Biol 236: 76-88
Dupé V, Lumsden A (2001) Hindbrain patterning involves graded responses to retinoic acid signalling. Development 128: 2199-208
Zeltser LM, Larsen CW, Lumsden A (2001) A new developmental compartment in the forebrain regulated by Lunatic fringe. Nat Neurosci 4: 683-4
Larsen CW, Zeltser LM, Lumsden A (2001) Boundary formation and compartition in the avian diencephalon. J Neurosci 21: 4699-711
Jungbluth S, Larsen C, Wizenmann A, Lumsden A (2001) Cell mixing between the embryonic midbrain and hindbrain. Curr Biol 11: 204-7
Schubert FR, Dietrich S, Mootoosamy RC, Chapman SC, Lumsden A (2001) Lbx1 marks a subset of interneurons in chick hindbrain and spinal cord. Mech Dev 101: 181-5
Chapman SC, Collignon J, Schoenwolf GC, Lumsden A (2001) Improved method for chick whole-embryo culture using a filter paper carrier. Dev Dyn 220: 284-9
Jungbluth S, Phelps C, Lumsden A (2001) CEPU-1 expression in the early embryonic chick brain. Mech Dev 101: 195-7
Lluís F, Roma J, Suelves M, Parra M, Aniorte G, Gallardo E, Illa I, Rodríguez L, Hughes SM, Carmeliet P, Roig M, Muñoz-Cánoves P (2001) Urokinase-dependent plasminogen activation is required for efficient skeletal muscle regeneration in vivo. Blood 97: 1703-11
Coutelle O, Blagden CS, Hampson R, Halai C, Rigby PW, Hughes SM (2001) Hedgehog signalling is required for maintenance of myf5 and myoD expression and timely terminal differentiation in zebrafish adaxial myogenesis. Dev Biol 236: 136-50
Heisenberg CP, Houart C, Take-Uchi M, Rauch GJ, Young N, Coutinho P, Masai I, Caneparo L, Concha ML, Geisler R, Dale TC, Wilson SW, Stemple DL (2001) A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon. Genes Dev 15: 1427-34
Barrett C, Guthrie S (2001) Expression patterns of the netrin receptor UNC5H1 among developing motor neurons in the embryonic rat hindbrain. Mech Dev 106: 163-6
Gavalas A, Trainor P, Ariza-McNaughton L, Krumlauf R (2001) Synergy between Hoxa1 and Hoxb1: the relationship between arch patterning and the generation of cranial neural crest. Development 128: 3017-27
Di Rocco G, Gavalas A, Popperl H, Krumlauf R, Mavilio F, Zappavigna V (2001) The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function. J Biol Chem 276: 20506-15
Yamada T, Okafuji T, Ohta K, Handwerker C, Drescher U, Tanaka H (2001) Analysis of ephrin-A2 in the chick retinotectal projection using a function-blocking monoclonal antibody. J Neurobiol 47: 245-54
Knöll B, Zarbalis K, Wurst W, Drescher U (2001) A role for the EphA family in the topographic targeting of vomeronasal axons. Development 128: 895-906
Knöll B, Isenmann S, Kilic E, Walkenhorst J, Engel S, Wehinger J, Bähr M, Drescher U (2001) Graded expression patterns of ephrin-As in the superior colliculus after lesion of the adult mouse optic nerve. Mech Dev 106: 119-27
Dunican DJ, Williams EJ, Howell FV, Doherty P (2001) Selective inhibition of fibroblast growth factor (FGF)-stimulated mitogenesis by a FGF receptor-1-derived phosphopeptide. Cell Growth Differ 12: 255-64
Dunican DJ, Doherty P (2001) Designing cell-permeant phosphopeptides to modulate intracellular signaling pathways. Biopolymers 60: 45-60
Williams G, Williams EJ, Doherty P (2001) Dimeric versions of two short N-cadherin binding motifs (HAVDI and INPISG) function as N-cadherin agonists. J Biol Chem 277: 4361-7
Williams EJ, Williams G, Howell FV, Skaper SD, Walsh FS, Doherty P (2001) Identification of an N-cadherin motif that can interact with the fibroblast growth factor receptor and is required for axonal growth. J Biol Chem 276: 43879-86
Utton MA, Eickholt B, Howell FV, Wallis J, Doherty P (2001) Soluble N-cadherin stimulates fibroblast growth factor receptor dependent neurite outgrowth and N-cadherin and the fibroblast growth factor receptor co-cluster in cells. J Neurochem 76: 1421-30
Cafferty WB, Gardiner NJ, Gavazzi I, Powell J, McMahon SB, Heath JK, Munson J, Cohen J, Thompson SW (2001) Leukemia inhibitory factor determines the growth status of injured adult sensory neurons. J Neurosci 21: 7161-70
Bahri SM, Chia W, Yang X (2001) Characterization and mutant analysis of the Drosophila sema 5c gene. Dev Dyn 221: 322-30
Cai Y, Chia W, Yang X (2001) A family of snail-related zinc finger proteins regulates two distinct and parallel mechanisms that mediate Drosophila neuroblast asymmetric divisions. EMBO J 20: 1704-14
Bahri SM, Chia W, Yang X (2001) The Drosophila homolog of human AF10/AF17 leukemia fusion genes (Dalf) encodes a zinc finger/leucine zipper nuclear protein required in the nervous system for maintaining EVE expression and normal growth. Mech Dev 100: 291-301
Helps NR, Cohen PT, Bahri SM, Chia W, Babu K (2001) Interaction with protein phosphatase 1 Is essential for bifocal function during the morphogenesis of the Drosophila compound eye. Mol Cell Biol 21: 2154-64
Tio M, Udolph G, Yang X, Chia W (2001) cdc2 links the Drosophila cell cycle and asymmetric division machineries. Nature 409: 1063-7
Udolph G, Rath P, Chia W (2001) A requirement for Notch in the genesis of a subset of glial cells in the Drosophila embryonic central nervous system which arise through asymmetric divisions. Development 128: 1457-66
Morin X, Daneman R, Zavortink M, Chia W (2001) A protein trap strategy to detect GFP-tagged proteins expressed from their endogenous loci in Drosophila. Proc Natl Acad Sci U S A 98: 15050-5
Altmann CR, Bell E, Sczyrba A, Pun J, Bekiranov S, Gaasterland T, Brivanlou AH (2001) Microarray-based analysis of early development in Xenopus laevis. Dev Biol 236: 64-75
Simeone A, Acampora D (2001) The role of Otx2 in organizing the anterior patterning in mouse. Int J Dev Biol 45: 337-45

2000

Schinder AF, Berninger B, Poo M (2000) Postsynaptic target specificity of neurotrophin-induced presynaptic potentiation. Neuron 25: 151-63
Grammatopoulos GA, Bell E, Toole L, Lumsden A, Tucker AS (2000) Homeotic transformation of branchial arch identity after Hoxa2 overexpression. Development 127: 5355-65
Alves PM, Nunes R, Zhang C, Maycock CD, Sonnewald U, Carrondo MJ, Santos H (2000) Metabolism of 3-(13)C-malate in primary cultures of mouse astrocytes. Dev Neurosci 22: 456-62
Pazman C, Mayes CA, Fanto M, Haynes SR, Mlodzik M (2000) Rasputin, the Drosophila homologue of the RasGAP SH3 binding protein, functions in ras- and Rho-mediated signaling. Development 127: 1715-25
Fanto M, Weber U, Strutt DI, Mlodzik M (2000) Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye. Curr Biol 10: 979-88
Roversi P, Blanc E, Vonrhein C, Evans G, Bricogne G (2000) Modelling prior distributions of atoms for macromolecular refinement and completion. Acta Crystallogr D Biol Crystallogr 56: 1316-23
Blanc E, Restori R, Schwarzenbach D, Burgi HB, Fortsch M, Venugopalan P, Ermer O (2000) Orientational disorder as a function of temperature in the clathrate structure of hydroquinone and C60 Acta Crystallogr B 56 (Pt 6): 1003-10
Stienstra CM, van Diepen MT, Joëls M (2000) Field responses to perforant path stimulation in the rat dentate gyrus: role of corticosterone and NMDA-receptor activation. Brain Res 854: 230-4
Roth S, Johansson M, Loukola A, Peltomäki P, Järvinen H, Mecklin JP, Aaltonen LA (2000) Mutation analysis of SMAD2, SMAD3, and SMAD4 genes in hereditary non-polyposis colorectal. J Med Genet 37: 298-300
Prinjha R, Moore SE, Vinson M, Blake S, Morrow R, Christie G, Michalovich D, Simmons DL, Walsh FS (2000) Inhibitor of neurite outgrowth in humans. Nature 403: 383-4
Harrison DC, Roberts J, Campbell CA, Crook B, Davis R, Deen K, Meakin J, Michalovich D, Price J, Stammers M, Maycox PR (2000) TR3 death receptor expression in the normal and ischaemic brain. Neuroscience 96: 147-60
Robbins MJ, Michalovich D, Hill J, Calver AR, Medhurst AD, Gloger I, Sims M, Middlemiss DN, Pangalos MN (2000) Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C). Genomics 67: 8-18
Ozaki K, Kikly K, Michalovich D, Young PR, Leonard WJ (2000) Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain. Proc Natl Acad Sci U S A 97: 11439-44
Kiecker C, Müller F, Wu W, Glinka A, Strähle U, Niehrs C (2000) Phenotypic effects in Xenopus and zebrafish suggest that one-eyed pinhead functions as antagonist of BMP signalling. Mech Dev 94: 37-46