Publications

2025

Schaubroeck S, Demurie E, Begum-Ali J, Bölte S, Boterberg S, Buitelaar J, Charman T, Falck-Ytter T, Hunnius S, Johnson MH, Jones E, Oosterling I, Pasco G, Pijl M, Van den Boomen C, Warreyn P, Roeyers H (2025) The stability of the Autism Diagnostic Observation Schedule-2 in children aged 14-36 months with elevated likelihood for autism. J Child Psychol Psychiatry

Mehra C, Beyh A, Laiou P, Garces P, Jones EJH, Mason L, Buitelaar J, Johnson MH, Murphy D, Loth E, Dell'Acqua F, Ewen JB, Richardson MP, O'Muircheartaigh J (2025) Zero-phase-delay synchrony between interacting neural populations: implications for functional connectivity-derived biomarkers. Imaging Neurosci (Camb)

Sifoglu D, Pereira B, DeGregory C, Shah R, Maier W, Guan J, Clark I, Patel D, Ch'ng Q, Alcedo J (2025) THE NEUROPEPTIDE NEUROMEDIN U RECEPTOR NMUR-1 BUFFERS INSULIN RECEPTOR SIGNALING IN BACTERIA-DEPENDENT C. ELEGANS SURVIVAL. bioRxiv

Sproston CJ, Rak JE, Marin EC, Kondo S, Williams DW (2025) Hemilineage-specific deployment of the pro-apoptotic RHG genes reaper and grim during neurogenesis sculpts segment and sex-specific neural network composition in Drosophila. Development

Tufo C, Cheah M, Lipovsek M, Byrne DJ, Kothandapani K, Browne LP, Grubb MS (2025) Functional Maturation and Experience-Dependent Plasticity in Adult-Born Olfactory Bulb Dopaminergic Neurons. Eur J Neurosci

Wu H, Constance W, Abe A, Kondo S, Williams D, Tanimoto H (2025) Spatial Gradient of Axon Terminal Maturation Reveals the Sequential Active Zone Assembly in Adult Drosophila Mushroom Bodies. MicroPubl Biol

Tang SS, Pellegrini L (2025) In preprints: primed for patterning - how epiblast cells encode the neural map in motion. Development

Armstrong CL, McLaughlin T, Hindges R, O'Leary DDM (2025) Misexpression of ephrin-B2 disrupts laminar patterning in chick optic tectum. Brain Struct Funct

Carolan J, Land MA, Lu X, Beau M, Kostadinov D, St-Pierre F, Clark BA, Häusser M (2025) All-optical voltage interrogation for probing synaptic plasticity in vivo. Nat Commun

Sadeh S, Clopath C (2025) The emergence of NeuroAI: bridging neuroscience and artificial intelligence. Nat Rev Neurosci

Gentile A, Stavropoulou K, Long KR (2025) ECM Mechanics in Central Nervous System Morphogenesis. Dev Neurosci

Long KR, Huttner WB, Namba T (2025) Neocortex Folding in Primates up to Human: Evolution and Mechanisms. Dev Neurosci

Yap K, Chung TH, Hedges EC, Nishimura AL, Shaw CE, Makeyev EV (2025) Enhanced hybridization-proximity labeling discovers protein interactomes of single RNA molecules. Nat Commun

Andreae LC, Kebschull JM, Zador AM (2025) Evolution and Development of Neural Circuits. Cold Spring Harb Perspect Biol

Lenherr C, Neves G, de Oliveira MG, Burrone J (2025) Bringing Chandelier Cells Out of the Shadows: Exploring the Development of a Unique Neuron Type in the Brain. Cold Spring Harb Perspect Biol

Selten M, Bernard C, Mukherjee D, Hamid F, Hanusz-Godoy A, Oozeer F, Zimmer C, Marín O (2025) Regulation of PV interneuron plasticity by neuropeptide-encoding genes. Nature

Laudańska Z, Caunt A, Cristia A, Warlaumont A, Patsis K, Tomalski P, Warreyn P, Abney DH, Borjon JI, Airaksinen M, Jones EJ, Bölte S, Dall M, Holzinger D, Poustka L, Roeyers H, Wass S, Zhang D, Marschik PB (2025) From data to discovery: Technology propels speech-language research and theory-building in developmental science. Neurosci Biobehav Rev

Marín O (2025) Development of GABAergic Interneurons in the Human Cerebral Cortex. Eur J Neurosci

Jézéquel J, Condomitti G, Kroon T, Hamid F, Sanalidou S, Garcés T, Maeso P, Balia M, Hu Z, Sahara S, Rico B (2025) Cadherins orchestrate specific patterns of perisomatic inhibition onto distinct pyramidal cell populations. Nat Commun

Tapia VS, Withers SE, Zhou R, Bennington A, Hoyle C, Hedley F, El Khouja A, Luka N, Massimo M, Crilly S, Long KR, Lawrence CB, Kasher PR (2025) The role of 25-hydroxycholesterol in the pathophysiology of brain vessel dysfunction associated with infection and cholesterol dysregulation. Dis Model Mech

Konishi K, Neves G, Russell M, Mimura M, Burrone J, Fleck R (2025) A workflow for semi-automated volume correlative light microscopy and transmission electron tomography. J Microsc

Knight SR, Abbasova L, Zeighami Y, Hansen JY, Martins D, Zelaya F, Dipasquale O, Liu T, Shin D, Bossong M, Azis M, Antoniades M, Howes OD, Bonoldi I, Egerton A, Allen P, O'Daly O, McGuire P, Modinos G (2025) Transcriptional and neurochemical signatures of cerebral blood flow alterations in schizophrenia and individuals at clinical high-risk for psychosis. Biol Psychiatry

Perochon T, Krsnik Z, Massimo M, Ruchiy Y, Romero AL, Mohammadi E, Li X, Long KR, Parkkinen L, Blomgren K, Lagache T, Menassa DA, Holcman D (2025) Unraveling microglial spatial organization in the developing human brain with DeepCellMap, a deep learning approach coupled with spatial statistics. Nat Commun

Araya C, Boekemeyer R, Farlie F, Moon L, Darwish F, Rookyard C, Allison L, Vizcay-Barrena G, Fleck R, Aranda M, Tada M, Clarke JDW (2025) An analysis of contractile and protrusive cell behaviors at the superficial surface of the zebrafish neural plate. Dev Dyn

Begum-Ali J, Mason L, Charman T, Johnson MH, Green J, Garg S, Jones EJH, (2025) Disrupted visual attention relates to cognitive development in infants with Neurofibromatosis Type 1. J Neurodev Disord

Tiantong Zhao , Laura Pellegrini, Bart van der Hee, Jos Boekhorst, Aline Fernandes, Sylvia Brugman, Peter van Baarlen and Jerry M. Wells (2025) Choroid plexus organoids reveal mechanisms of Streptococcus suis translocation at the blood-cerebrospinal fluid barrier Fluids and Barriers of the CNS

Tang SS, Apsley EJ, Pellegrini L (2025) Functional Imaging Methods for Investigating 3D Choroid Plexus Organoids. Methods Mol Biol

Marchica V, Biasetti L, Barnard J, Li S, Nikolaou N, Frosch MP, Lucente DE, Eldaief M, King A, Fanto M, Troakes C, Houart C, Smith BN (2025) Annexin A11 mutations are associated with nuclear envelope dysfunction in vivo and in human tissue. Brain

2024

Daniel J Lloyd-Davies Sánchez, Feline W Lindhout, Alexander J Anderson, Laura Pellegrini, Madeline A Lancaster (2024) Mouse brain organoids model in vivo neurodevelopment and function and capture differences to human bioRxiv

Kainov Y, Hamid F, Makeyev EV (2024) Recurrent disruption of tumour suppressor genes in cancer by somatic mutations in cleavage and polyadenylation signals. Elife

Hopkins PCR, Troakes C, King A, Tear G (2024) Transmembrane and coiled-coil 2 associates with Alzheimer's disease pathology in the human brain. Brain Pathol

Best AJ, Braunschweig U, Wu M, Farhangmehr S, Pasculescu A, Lim JJ, Comsa LC, Jen M, Wang J, Datti A, Wrana JL, Cordes SP, Al-Awar R, Han H, Blencowe BJ (2024) High-throughput sensitive screening of small molecule modulators of microexon alternative splicing using dual Nano and Firefly luciferase reporters. Nat Commun
Lim JJ, Vining KH, Mooney DJ, Blencowe BJ (2024) Matrix stiffness-dependent regulation of immunomodulatory genes in human MSCs is associated with the lncRNA CYTOR. Proc Natl Acad Sci U S A
Ni Z, Ahmed N, Nabeel-Shah S, Guo X, Pu S, Song J, Marcon E, Burke GL, Tong AHY, Chan K, Ha KCH, Blencowe BJ, Moffat J, Greenblatt JF (2024) Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter. Nucleic Acids Res
Zhuravskaya A, Yap K, Hamid F, Makeyev EV (2024) Alternative splicing coupled to nonsense-mediated decay coordinates downregulation of non-neuronal genes in developing mouse neurons. Genome Biol

Horton S, Mastrolia V, Jackson RE, Kemlo S, Pereira Machado PM, Carbajal MA, Hindges R, Fleck RA, Aguiar P, Neves G, Burrone J (2024) Excitatory and inhibitory synapses show a tight subcellular correlation that weakens over development. Cell Rep

Li JD, Taipale M, Blencowe BJ (2024) Efficient, specific, and combinatorial control of endogenous exon splicing with dCasRx-RBM25. Mol Cell
Mateus JC, Sousa MM, Burrone J, Aguiar P (2024) Beyond a Transmission Cable-New Technologies to Reveal the Richness in Axonal Electrophysiology. J Neurosci

Marín O (2024) Parvalbumin interneuron deficits in schizophrenia. Eur Neuropsychopharmacol

Gogou C, Beugelink JW, Frias CP, Kresik L, Jaroszynska N, Drescher U, Janssen BJC, Hindges R, Meijer DH (2024) Alternative splicing controls teneurin-3 compact dimer formation for neuronal recognition. Nat Commun

Pellegrini L, Silva-Vargas V, Patrizi A (2024) Breakthroughs in choroid plexus and CSF biology from the first European Choroid plexus Scientific Forum (ECSF). Fluids Barriers CNS

Li S, Shea QTK, Ling YT, Zheng YP (2024) Investigation of 3D vessel reconstruction under Doppler imaging with phantoms: Towards reconstruction of the Circle of Willis. Ultrasonics

Pérez-Sisqués L, Bhatt SU, Matuleviciute R, Gileadi TE, Kramar E, Graham A, Garcia FG, Keiser A, Matheos DP, Cain JA, Pittman AM, Andreae LC, Fernandes C, Wood MA, Giese KP, Basson MA (2024) The Intellectual Disability Risk Gene Kdm5b Regulates Long-Term Memory Consolidation in the Hippocampus. J Neurosci

Ellingford RA, Tojo M, Basson MA, Andreae LC (2024) Male-Dominant Effects of Chd8 Haploinsufficiency on Synaptic Phenotypes during Development in Mouse Prefrontal Cortex. ACS Chem Neurosci

Cole N, Harvey M, Myers-Joseph D, Gilra A, Khan A (2024) Prediction error signals in anterior cingulate cortex drive task-switching bioRxiv

Mòdol L, Moissidis M, Selten M, Oozeer F, Marín O (2024) Somatostatin interneurons control the timing of developmental desynchronization in cortical networks. Neuron

Folgueira M, Clarke JDW (2024) Telencephalic eversion in embryos and early larvae of four teleost species. Evol Dev

Cubillos P, Ditzer N, Kolodziejczyk A, Schwenk G, Hoffmann J, Schütze TM, Derihaci RP, Birdir C, Köllner JE, Petzold A, Sarov M, Martin U, Long KR, Wimberger P, Albert M (2024) The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex. EMBO J

Makeyev EV, Huang S (2024) The perinucleolar compartment: structure, function, and utility in anti-cancer drug development. Nucleus

Read E, Hindges R (2024) A novel locomotion-based prepulse inhibition assay in zebrafish larvae. MicroPubl Biol

Ganier C, Mazin P, Herrera-Oropeza G, Du-Harpur X, Blakeley M, Gabriel J, Predeus AV, Cakir B, Prete M, Harun N, Darrigrand JF, Haiser A, Wyles S, Shaw T, Teichmann SA, Haniffa M, Watt FM, Lynch MD (2024) Multiscale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma. Proc Natl Acad Sci U S A

Rodríguez-Moreno CB, Cañeque-Rufo H, Flor-García M, Terreros-Roncal J, Moreno-Jiménez EP, Pallas-Bazarra N, Bressa C, Larrosa M, Cafini F, Llorens-Martín M (2024) Azithromycin preserves adult hippocampal neurogenesis and behavior in a mouse model of sepsis. Brain Behav Immun

Fisher J, Verhagen M, Long Z, Moissidis M, Yan Y, He C, Wang J, Micoli E, Alastruey CM, Moors R, Marín O, Mi D, Lim L (2024) Cortical somatostatin long-range projection neurons and interneurons exhibit divergent developmental trajectories. Neuron

Myers-Joseph D, Wilmes KA, Fernandez-Otero M, Clopath C, Khan AG (2024) Disinhibition by VIP interneurons is orthogonal to cross-modal attentional modulation in primary visual cortex. Neuron

2023

Sinitcyn P, Richards AL, Weatheritt RJ, Brademan DR, Marx H, Shishkova E, Meyer JG, Hebert AS, Westphall MS, Blencowe BJ, Cox J, Coon JJ (2023) Global detection of human variants and isoforms by deep proteome sequencing. Nat Biotechnol
Cui H, Diedrich JK, Wu DC, Lim JJ, Nottingham RM, Moresco JJ, Yates JR, Blencowe BJ, Lambowitz AM, Schimmel P (2023) Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2. Nat Cell Biol
Roth JF, Braunschweig U, Wu M, Li JD, Lin ZY, Larsen B, Weatheritt RJ, Gingras AC, Blencowe BJ (2023) Systematic analysis of alternative exon-dependent interactome remodeling reveals multitasking functions of gene regulatory factors. Mol Cell
Cheesbrough A, Harley P, Riccio F, Wu L, Song W, Lieberam I (2023) A scalable human iPSC-based neuromuscular disease model on suspended biobased elastomer nanofiber scaffolds. Biofabrication

Mishra S, Dabaja M, Akhlaq A, Pereira B, Marbach K, Rovcanin M, Chandra R, Caballero A, Fernandes de Abreu D, Ch'ng Q, Alcedo J (2023) Specific sensory neurons and insulin-like peptides modulate food type-dependent oogenesis and fertilization in Caenorhabditis elegans. Elife

Zeng B, Liu Z, Lu Y, Zhong S, Qin S, Huang L, Zeng Y, Li Z, Dong H, Shi Y, Yang J, Dai Y, Ma Q, Sun L, Bian L, Han D, Chen Y, Qiu X, Wang W, Marín O, Wu Q, Wang Y, Wang X (2023) The single-cell and spatial transcriptional landscape of human gastrulation and early brain development. Cell Stem Cell

Kainov Y, Zhuravskaya A, Makeyev EV (2023) Protocol for auxin-inducible depletion of the RNA-binding protein PTBP1 in mouse embryonic stem cells. STAR Protoc

Beltrán Arranz A, Berninger B (2023) Seizing hope: Advancing cell therapy for pharmaco-resistant epilepsy toward the clinic. Cell Stem Cell

Felske T, Tocco C, Péron S, Harb K, Alfano C, Galante C, Berninger B, Studer M (2023) Lmo4 synergizes with Fezf2 to promote direct in vivo reprogramming of upper layer cortical neurons and cortical glia towards deep-layer neuron identities. PLoS Biol

Chadwick A, Khan AG, Poort J, Blot A, Hofer SB, Mrsic-Flogel TD, Sahani M (2023) Learning shapes cortical dynamics to enhance integration of relevant sensory input. Neuron

Choi S, Schilder BM, Abbasova L, Murphy AE, Skene NG (2023) EpiCompare: R package for the comparison and quality control of epigenomic peak files. Bioinform Adv

Puhl CJ, Wefelmeyer W, Burrone J (2023) Cholinergic Stimulation Modulates the Functional Composition of CA3 Cell Types in the Hippocampus. J Neurosci

Williams J, Hurling C, Munir S, Harley P, Machado CB, Cujba AM, Alvarez-Fallas M, Danovi D, Lieberam I, Sancho R, Beales P, Watt FM (2023) Modelling renal defects in Bardet-Biedl syndrome patients using human iPS cells. Front Cell Dev Biol

Fan W, Jurado-Arjona J, Alanis-Lobato G, Péron S, Berger C, Andrade-Navarro MA, Falk S, Berninger B (2023) The transcriptional co-activator Yap1 promotes adult hippocampal neural stem cell activation. EMBO J

Compans B, Burrone J (2023) Chandelier cells shine a light on the formation of GABAergic synapses. Curr Opin Neurobiol

Harley P, Paredes-Redondo A, Grenci G, Viasnoff V, Lin YY, Lieberam I (2023) 3D Compartmentalised Human Pluripotent Stem Cell-derived Neuromuscular Co-cultures. Bio Protoc

Jetsonen E, Didio G, Winkel F, Llach Pou M, Boj C, Kuczynski-Noyau L, Võikar V, Guirado R, Taira T, Lauri SE, Castrén E, Umemori J (2023) Activation of TrkB in Parvalbumin interneurons is required for the promotion of reversal learning in spatial and fear memory by antidepressants. Neuropsychopharmacology

Iannone C, Kainov Y, Zhuravskaya A, Hamid F, Nojima T, Makeyev EV (2023) PTBP1-activated co-transcriptional splicing controls epigenetic status of pluripotent stem cells. Mol Cell

Massimo M, Barelli C, Moreno C, Collesi C, Holloway RK, Crespo B, Zentilin L, Williams A, Miron VE, Giacca M, Long KR (2023) Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection. Brain

Poopalasundaram S, Richardson J, Graham A (2023) Key separable events in the remodelling of the pharyngeal arches. J Anat

Berzanskyte I, Riccio F, Machado CB, Bradbury EJ, Lieberam I (2023) Enrichment of human embryonic stem cell-derived V3 interneurons using an Nkx2-2 gene-specific reporter. Sci Rep

Kebschull JM, Casoni F, Consalez GG, Goldowitz D, Hawkes R, Ruigrok TJH, Schilling K, Wingate R, Wu J, Yeung J, Uusisaari MY (2023) Cerebellum Lecture: the Cerebellar Nuclei-Core of the Cerebellum. Cerebellum.

Cameron D, Mi D, Vinh NN, Webber C, Li M, Marín O, O'Donovan MC, Bray NJ (2023) Single-Nuclei RNA Sequencing of 5 Regions of the Human Prenatal Brain Implicates Developing Neuron Populations in Genetic Risk for Schizophrenia. Biol Psychiatry

2022

Nabeel-Shah S, Lee H, Ahmed N, Burke GL, Farhangmehr S, Ashraf K, Pu S, Braunschweig U, Zhong G, Wei H, Tang H, Yang J, Marcon E, Blencowe BJ, Zhang Z, Greenblatt JF (2022) SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response. iScience
Barutcu AR, Wu M, Braunschweig U, Dyakov BJA, Luo Z, Turner KM, Durbic T, Lin ZY, Weatheritt RJ, Maass PG, Gingras AC, Blencowe BJ (2022) Systematic mapping of nuclear domain-associated transcripts reveals speckles and lamina as hubs of functionally distinct retained introns. Mol Cell
Fagg WS, Liu N, Braunschweig U, Pereira de Castro KL, Chen X, Ditmars FS, Widen SG, Donohue JP, Modis K, Russell WK, Fair JH, Weirauch MT, Blencowe BJ, Garcia-Blanco MA (2022) Definition of germ layer cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fate. Nucleic Acids Res