Publications

2002

Ellies DL, Tucker AS, Lumsden A (2002) Apoptosis of premigratory neural crest cells in rhombomeres 3 and 5: consequences for patterning of the branchial region. Dev Biol 251: 118-28
Chapman SC, Schubert FR, Schoenwolf GC, Lumsden A (2002) Analysis of spatial and temporal gene expression patterns in blastula and gastrula stage chick embryos. Dev Biol 245: 187-99
Chargé SB, Brack AS, Hughes SM (2002) Aging-related satellite cell differentiation defect occurs prematurely after Ski-induced muscle hypertrophy. Am J Physiol Cell Physiol 283: C1228-41
Krylova O, Herreros J, Cleverley KE, Ehler E, Henriquez JP, Hughes SM, Salinas PC (2002) WNT-3, expressed by motoneurons, regulates terminal arborization of neurotrophin-3-responsive spinal sensory neurons. Neuron 35: 1043-56
Houart C, Caneparo L, Heisenberg C, Barth K, Take-Uchi M, Wilson S (2002) Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling. Neuron 35: 255-65
Grandel H, Lun K, Rauch GJ, Rhinn M, Piotrowski T, Houart C, Sordino P, Küchler AM, Schulte-Merker S, Geisler R, Holder N, Wilson SW, Brand M (2002) Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud. Development 129: 2851-65
Naeem A, Abbas L, Guthrie S (2002) Comparison of the effects of HGF, BDNF, CT-1, CNTF, and the branchial arches on the growth of embryonic cranial motor neurons. J Neurobiol 51: 101-14
Khan Z, Ferrari G, Kasper M, Tonge DA, Steiner JP, Hamilton GS, Gordon-Weeks PR (2002) The non-immunosuppressive immunophilin ligand GPI-1046 potently stimulates regenerating axon growth from adult mouse dorsal root ganglia cultured in Matrigel. Neuroscience 114: 601-9
Hall AC, Brennan A, Goold RG, Cleverley K, Lucas FR, Gordon-Weeks PR, Salinas PC (2002) Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons. Mol Cell Neurosci 20: 257-70
Gonzalez-Billault C, Owen R, Gordon-Weeks PR, Avila J (2002) Microtubule-associated protein 1B is involved in the initial stages of axonogenesis in peripheral nervous system cultured neurons. Brain Res 943: 56-67
Dieterich DC, Trivedi N, Engelmann R, Gundelfinger ED, Gordon-Weeks PR, Kreutz MR (2002) Partial regeneration and long-term survival of rat retinal ganglion cells after optic nerve crush is accompanied by altered expression, phosphorylation and distribution of cytoskeletal proteins. Eur J Neurosci 15: 1433-43
van Horck FP, Lavazais E, Eickholt BJ, Moolenaar WH, Divecha N (2002) Essential role of type I(alpha) phosphatidylinositol 4-phosphate 5-kinase in neurite remodeling. Curr Biol 12: 241-5
Sakurai T, Wong E, Drescher U, Tanaka H, Jay DG (2002) Ephrin-A5 restricts topographically specific arborization in the chick retinotectal projection in vivo. Proc Natl Acad Sci U S A 99: 10795-800
Eickholt BJ, Walsh FS, Doherty P (2002) An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling. J Cell Biol 157: 211-7
Chadborn N, Eickholt B, Doherty P, Bolsover S (2002) Direct measurement of local raised subplasmalemmal calcium concentrations in growth cones advancing on an N-cadherin substrate. Eur J Neurosci 15: 1891-8
Buescher M, Hing FS, Chia W (2002) Formation of neuroblasts in the embryonic central nervous system of Drosophila melanogaster is controlled by SoxNeuro. Development 129: 4193-203
Yu F, Ong CT, Chia W, Yang X (2002) Membrane targeting and asymmetric localization of Drosophila partner of inscuteable are discrete steps controlled by distinct regions of the protein. Mol Cell Biol 22: 4230-40
Altmann CR, Chang C, Muñoz-Sanjuán I, Bell E, Heke M, Rifkin DB, Brivanlou AH (2002) The latent-TGFbeta-binding-protein-1 (LTBP-1) is expressed in the organizer and regulates nodal and activin signaling. Dev Biol 248: 118-27
Studer M (2002) Initiation of facial motoneurone migration is dependent on rhombomeres 5 and 6. Development 128: 3707-16
Reichert H, Simeone A (2002) Developmental genetic evidence for a monophyletic origin of the bilaterian brain. Philos Trans R Soc Lond B Biol Sci 356: 1533-44
Martinez-Barbera JP, Signore M, Boyl PP, Puelles E, Acampora D, Gogoi R, Schubert F, Lumsden A, Simeone A (2002) Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2. Development 128: 4789-800
Patel K, Nash JA, Itoh A, Liu Z, Sundaresan V, Pini A (2002) Slit proteins are not dominant chemorepellents for olfactory tract and spinal motor axons. Development 128: 5031-7
Reimers D, López-Toledano MA, Mason I, Cuevas P, Redondo C, Herranz AS, Lobo MV, Bazán E (2002) Developmental expression of fibroblast growth factor (FGF) receptors in neural stem cell progeny. Modulation of neuronal and glial lineages by basic FGF treatment. Neurol Res 23: 612-21
Berkovitz BK, Maden M, McCaffery P, Barrett AW (2002) The distribution of retinaldehyde dehydrogenase-2 in rat and human orodental tissues. Arch Oral Biol 46: 1099-104
Schubert FR, Tremblay P, Mansouri A, Faisst AM, Kammandel B, Lumsden A, Gruss P, Dietrich S (2002) Early mesodermal phenotypes in splotch suggest a role for Pax3 in the formation of epithelial somites. Dev Dyn 222: 506-21
Goold RG, Gordon-Weeks PR (2002) Microtubule-associated protein 1B phosphorylation by glycogen synthase kinase 3beta is induced during PC12 cell differentiation. J Cell Sci 114: 4273-84
Menon SD, Chia W (2002) Drosophila rolling pebbles: a multidomain protein required for myoblast fusion that recruits D-Titin in response to the myoblast attractant Dumbfounded. Dev Cell 1: 691-703
Sancini G, Franceschetti S, Lavazza T, Panzica F, Cipelletti B, Frassoni C, Spreafico R, Acampora D, Avanzini G (2002) Potentially epileptogenic dysfunction of cortical NMDA- and GABA-mediated neurotransmission in Otx1-/- mice. Eur J Neurosci 14: 1065-74

2001

Brünig I, Penschuck S, Berninger B, Benson J, Fritschy JM (2001) BDNF reduces miniature inhibitory postsynaptic currents by rapid downregulation of GABA(A) receptor surface expression. Eur J Neurosci 13: 1320-8
Avner P, Bruls T, Poras I, Eley L, Gas S, Ruiz P, Wiles MV, Sousa-Nunes R, Kettleborough R, Rana A, Morissette J, Bentley L, Goldsworthy M, Haynes A, Herbert E, Southam L, Lehrach H, Weissenbach J, Manenti G, Rodriguez-Tome P, Beddington R, Dunwoodie S, C (2001) A radiation hybrid transcript map of the mouse genome. Nat Genet 29: 194-200
Chambers D (2001) Scientists signal the way forward. Trends Genet 17: 309-10
Stephen RL, Shaw LE, Larsen C, Corcoran D, Darbre PD (2001) Insulin-like growth factor receptor levels are regulated by cell density and by long term estrogen deprivation in MCF7 human breast cancer cells. J Biol Chem 276: 40080-6
Echeverri K, Clarke JD, Tanaka EM (2001) In vivo imaging indicates muscle fiber dedifferentiation is a major contributor to the regenerating tail blastema. Dev Biol 236: 151-64
Meyer MP, Swann K, Burnstock G, Clarke JD (2001) The extracellular ATP receptor, cP2Y(1), inhibits cartilage formation in micromass cultures of chick limb mesenchyme. Dev Dyn 222: 494-505
Harsum S, Clarke JD, Martin P (2001) A reciprocal relationship between cutaneous nerves and repairing skin wounds in the developing chick embryo. Dev Biol 238: 27-39
Chen LF, Blanc E, Chapman MS, Taylor KA (2001) Real space refinement of acto-myosin structures from sectioned muscle. J Struct Biol 133: 221-32
Retailleau P, Yin Y, Hu M, Roach J, Bricogne G, Vonrhein C, Roversi P, Blanc E, Sweet RM, Carter CW (2001) High-resolution experimental phases for tryptophanyl-tRNA synthetase (TrpRS) complexed with tryptophanyl-5'AMP. Acta Crystallogr D Biol Crystallogr 57: 1595-608
Lehto M, Laitinen S, Chinetti G, Johansson M, Ehnholm C, Staels B, Ikonen E, Olkkonen VM (2001) The OSBP-related protein family in humans. J Lipid Res 42: 1203-13
Zhu Y, Michalovich D, Wu H, Tan KB, Dytko GM, Mannan IJ, Boyce R, Alston J, Tierney LA, Li X, Herrity NC, Vawter L, Sarau HM, Ames RS, Davenport CM, Hieble JP, Wilson S, Bergsma DJ, Fitzgerald LR (2001) Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Mol Pharmacol 59: 434-41
Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CG, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harri (2001) AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1. J Biol Chem 276: 28969-75
Kiecker C, Niehrs C (2001) The role of prechordal mesendoderm in neural patterning. Curr Opin Neurobiol 11: 27-33
Kiecker C, Niehrs C (2001) A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus. Development 128: 4189-201
Scholpp S, Brand M (2001) Morpholino-induced knockdown of zebrafish engrailed genes eng2 and eng3 reveals redundant and unique functions in midbrain--hindbrain boundary development. Genesis 30: 129-33
Eickholt BJ, Graham A, Lumsden A, Wizenmann A (2001) Rhombomere interactions control the segmental differentiation of hindbrain neurons. Mol Cell Neurosci 18: 141-8
Krug K, Akerman CJ, Thompson ID (2001) Responses of neurons in neonatal cortex and thalamus to patterned visual stimulation through the naturally closed lids. J Neurophysiol 85: 1436-43
Burrone J, Murthy VN (2001) Synaptic plasticity: rush hour traffic in the AMPA lanes. Curr Biol 11: R274-7
Leibowitz G, Melloul D, Yuli M, Gross DJ, Apelqvist A, Edlund H, Cerasi E, Kaiser N (2001) Defective glucose-regulated insulin gene expression associated with PDX-1 deficiency in the Psammomys obesus model of type 2 diabetes. Diabetes 50 Suppl 1: S138-9
Leibowitz G, Ferber S, Apelqvist A Edlund H, Gross DJ, Cerasi E, Melloul D, Kaiser N (2001) IPF1/PDX1 deficiency and beta-cell dysfunction in Psammomys obesus, an animal With type 2 diabetes. Diabetes 50: 1799-806
Basson MA, Zamoyska R (2001) Insights into T-cell development from studies using transgenic and knockout mice. Mol Biotechnol 18: 11-23
Mason I, Chambers D, Shamim H, Walshe J, Irving C (2001) Regulation and function of FGF8 in patterning of midbrain and anterior hindbrain. Biochem Cell Biol 78: 577-84
Gustafson AL, Mason I (2001) Expression of receptor tyrosine phosphatase gamma during early development of the chick embryo. Mech Dev 98: 183-6
Reifers F, Adams J, Mason IJ, Schulte-Merker S, Brand M (2001) Overlapping and distinct functions provided by fgf17, a new zebrafish member of the Fgf8/17/18 subgroup of Fgfs. Mech Dev 99: 39-49
Graham A (2001) The evolution of the vertebrates--genes and development. Curr Opin Genet Dev 10: 624-8
Graham A, Smith A (2001) Patterning the pharyngeal arches. Bioessays 23: 54-61
Graham A (2001) The development and evolution of the pharyngeal arches. J Anat 199: 133-41
Graham A (2001) Development. Hear, hear, for the inner ear. Science 290: 1904-5
Smith A, Graham A (2001) Restricting Bmp-4 mediated apoptosis in hindbrain neural crest. Dev Dyn 220: 276-83
McGonnell IM, McKay IJ, Graham A (2001) A population of caudally migrating cranial neural crest cells: functional and evolutionary implications. Dev Biol 236: 354-63
Wingate RJ (2001) The rhombic lip and early cerebellar development. Curr Opin Neurobiol 11: 82-8
Tear G (2001) A new code for axons. Nature 409: 472-3
Acampora D, Gulisano M, Broccoli V, Simeone A (2001) Otx genes in brain morphogenesis. Prog Neurobiol 64: 69-95
Hughes SM (2001) Muscle development: reversal of the differentiated state. Curr Biol 11: R237-9
Hampson R, Hughes SM (2001) Muscular expressions: profiling genes in complex tissues. Genome Biol 2: REVIEWS1033
Guthrie S (2001) Axon guidance: Robos make the rules. Curr Biol 11: R300-3
Jacob J, Hacker A, Guthrie S (2001) Mechanisms and molecules in motor neuron specification and axon pathfinding. Bioessays 23: 582-95
Kinrade EF, Brates T, Tear G, Hidalgo A (2001) Roundabout signalling, cell contact and trophic support confine longitudinal glia and axons in the Drosophila CNS. Development 128: 207-16
Fritzsch B, Signore M, Simeone A, Fritzsch B (2001) Otx1 null mutant mice show partial segregation of sensory epithelia comparable to lamprey ears. Dev Genes Evol 211: 388-96
Acampora D, Boyl PP, Martinez-Barbera JP, Annino A, Signore M, Simeone A (2001) Otx genes in evolution: are they involved in instructing the vertebrate brain morphology? J Anat 199: 53-62
Boyl PP, Signore M, Annino A, Barbera JP, Acampora D, Simeone A (2001) Otx genes in the development and evolution of the vertebrate brain. Int J Dev Neurosci 19: 353-63
Martinez-Morales JR, Signore M, Acampora D, Simeone A, Bovolenta P (2001) Otx genes are required for tissue specification in the developing eye. Development 128: 2019-30
Rashid T, Banerjee M, Nikolic M (2001) Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology. J Biol Chem 276: 49043-52
Schneider RA, Hu D, Rubenstein JL, Maden M, Helms JA (2001) Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining FGF8 and SHH. Development 128: 2755-67
Schmidt C, Christ B, Maden M, Brand-Saberi B, Patel K (2001) Regulation of Epha4 expression in paraxial and lateral plate mesoderm by ectoderm-derived signals. Dev Dyn 220: 377-86
Bell E, Ensini M, Gulisano M, Lumsden A (2001) Dynamic domains of gene expression in the early avian forebrain. Dev Biol 236: 76-88
Dupé V, Lumsden A (2001) Hindbrain patterning involves graded responses to retinoic acid signalling. Development 128: 2199-208
Zeltser LM, Larsen CW, Lumsden A (2001) A new developmental compartment in the forebrain regulated by Lunatic fringe. Nat Neurosci 4: 683-4
Larsen CW, Zeltser LM, Lumsden A (2001) Boundary formation and compartition in the avian diencephalon. J Neurosci 21: 4699-711
Jungbluth S, Larsen C, Wizenmann A, Lumsden A (2001) Cell mixing between the embryonic midbrain and hindbrain. Curr Biol 11: 204-7
Schubert FR, Dietrich S, Mootoosamy RC, Chapman SC, Lumsden A (2001) Lbx1 marks a subset of interneurons in chick hindbrain and spinal cord. Mech Dev 101: 181-5
Chapman SC, Collignon J, Schoenwolf GC, Lumsden A (2001) Improved method for chick whole-embryo culture using a filter paper carrier. Dev Dyn 220: 284-9
Jungbluth S, Phelps C, Lumsden A (2001) CEPU-1 expression in the early embryonic chick brain. Mech Dev 101: 195-7
Lluís F, Roma J, Suelves M, Parra M, Aniorte G, Gallardo E, Illa I, Rodríguez L, Hughes SM, Carmeliet P, Roig M, Muñoz-Cánoves P (2001) Urokinase-dependent plasminogen activation is required for efficient skeletal muscle regeneration in vivo. Blood 97: 1703-11
Coutelle O, Blagden CS, Hampson R, Halai C, Rigby PW, Hughes SM (2001) Hedgehog signalling is required for maintenance of myf5 and myoD expression and timely terminal differentiation in zebrafish adaxial myogenesis. Dev Biol 236: 136-50
Heisenberg CP, Houart C, Take-Uchi M, Rauch GJ, Young N, Coutinho P, Masai I, Caneparo L, Concha ML, Geisler R, Dale TC, Wilson SW, Stemple DL (2001) A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon. Genes Dev 15: 1427-34
Barrett C, Guthrie S (2001) Expression patterns of the netrin receptor UNC5H1 among developing motor neurons in the embryonic rat hindbrain. Mech Dev 106: 163-6