Guy Tear

Guy Tear

Professor of Molecular Neurobiology, Head of Department of Genetics Education, Group leader



Biography:

Guy Tear studied Natural Sciences at Cambridge University (1983-1986) where he specialised in molecular biology topics within the Zoology Department. He remained at Cambridge for his PhD within the Genetics Department (1986-1990) investigating the genetic control of early development of the embryo. He moved to the University of California, Berkeley as a postdoctoral scientist training in the laboratory of Corey S Goodman. Guy participated in the discovery and characterisation of some of the first molecules which direct nerve cell growth during the ‘wiring up’ of the nervous system. In 1995 Guy joined the Biochemistry Department at Imperial College as an MRC Senior Research Fellow. In 1999 he was recruited to Kings to join the MRC Centre for Developmental Neurobiology and was promoted to Professor in 2004. Guy was head of the King’s College, London Department of Biochemistry from 2007 until 2014, and is currently head of the Genetics Department. Guy has held several awards including EMBO Long Term Fellowship (1991), American Cancer Society Fellow (1993) MRC Senior Non-clinical Fellow (1995). Guy is an editor for PLoS One and Frontiers in Neurodegenerative Diseases.

Links:

Thompson Reuters Researcher ID: C-5444-2009
KCL PURE: https://kclpure.kcl.ac.uk/portal/guy.tear.html

Selected publications:

Connolly KJ, O'Hare MB, Mohammed A, Aitchison KM, Anthoney NC, Taylor MJ, Stewart BA, Tuxworth RI, Tear G (2019) The neuronal ceroid lipofuscinosis protein Cln7 functions in the postsynaptic cell to regulate synapse development. Sci Rep 9: 15592
Bibollet-Bahena O, Okafuji T, Hokamp K, Tear G, Mitchell KJ (2017) A dual-strategy expression screen for candidate connectivity labels in the developing thalamus. PLoS One 12: e0177977
Mohammed A, O'Hare MB, Warley A, Tear G, Tuxworth RI (2017) in vivo localization of the neuronal ceroid lipofuscinosis proteins, CLN3 and CLN7, at endogenous expression levels. Neurobiol Dis 103: 123-132

Cate MS, Gajendra S, Alsbury S, Raabe T, Tear G, Mitchell KJ (2016) Mushroom body defect is required in parallel to Netrin for midline axon guidance in Drosophila. Development 143: 972-7