Adrian Pini

Adrian Pini

Senior Lecturer, Group leader



Biography:

Adrian Pini graduated in physiology and dental surgery from Guy’s Hospital London and was Bayliss Starling memorial Scholar at UCL where he took his doctorate. He then completed post-doctoral fellowships in Cambridge (MRC Training Fellow), Columbia (MRC Travelling Fellow) and at McGill working with Albert Aguayo. He has worked on the electrophysiology of peripheral nerve and spinal cord and is best known for his discovery of chemorepulsion in the developing nervous system. It was during these investigations that his group discovered the neurotoxic effects of histone H1. He has broadcast on radio and commented in the media about neural development and degeneration.

Links:

Thompson Reuters Researcher ID: C-5342-2009
KCL PURE: https://kclpure.kcl.ac.uk/portal/en/persons/adrian-pini(ee73a182-eb7b-414c-ad07-6c00297fe9b7).html

Selected publications:

Gilthorpe JD, Oozeer F, Nash J, Calvo M, Bennett DLH, Lumsden A, Pini A (2013) Extracellular histone H1 is neurotoxic and drives a pro-inflammatory response in microglia F1000Research 2:148
Campion C, Gilthorpe J, Gogoi R, and Pini A (2012) Sulfated oligosaccharides for use in treatment of neurodegenerative diseases Published patent WO 2012160337

Liu Z, Patel K, Schmidt H, Andrews W, Pini A, Sundaresan V (2004) Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding. Mol Cell Neurosci 26: 232-40
Knöll B, Schmidt H, Andrews W, Guthrie S, Pini A, Sundaresan V, Drescher U (2003) On the topographic targeting of basal vomeronasal axons through Slit-mediated chemorepulsion. Development 130: 5073-82