Sarah Guthrie

Sarah Guthrie

Visiting Professor, Group leader



Biography:

Sarah Guthrie studied Natural Sciences at Newnham College Cambridge, and obtained her PhD in Developmental Biology from University College London, studying intercellular communication in the amphibian embryo with Anne Warner. She won a Beit Memorial Fellowship to continue studies at UCL, and then completed postdoctoral work at Scripps Clinic in San Diego, USA, working with Bernie Gilula. She returned to the UK in 1989 to work with Andrew Lumsden on segmentation of the hindbrain, in Guy’s Hospital Medical School, where in 1991 she obtained a lectureship. Following the merger with King’s College London, she was one of the founder labs in the MRC Centre for Developmental Neurobiology in 2000, and obtained her Professorship in 2003. She is an expert on motor neuron development and has made important discoveries in brainstem patterning and axon guidance.

Sarah is Deputy Head of the Division of Neuroscience (Education), co-ordinating Neuroscience education across Undergraduate, Postgraduate taught and research programmes. She has contributed extensively to the development of bioscience education in King’s, including inception of the Neuroscience BSc programme and teaching department.

Links:

Thompson Reuters Researcher ID: C-5727-2009
KCL PURE: https://kclpure.kcl.ac.uk/portal/sarah.guthrie.html

Selected publications:

Montague K, Guthrie S, Poparic I (2017) In Vivo and In Vitro Knockdown Approaches in the Avian Embryo as a Means to Study Semaphorin Signaling. Methods Mol Biol 1493: 403-416
Zakaria S, Mao Y, Kuta A, de Sousa CF, Gaufo GO, McNeill H, Hindges R, Guthrie S, Irvine KD, Francis-West PH (2014) Regulation of neuronal migration by Dchs1-Fat4 planar cell polarity. Curr Biol 24: 1620-1627
Astick M, Tubby K, Mubarak WM, Guthrie S, Price SR (2014) Central topography of cranial motor nuclei controlled by differential cadherin expression. Curr Biol 24: 2541-7
Tripathi VB, Baskaran P, Shaw CE, Guthrie S (2014) Tar DNA-binding protein-43 (TDP-43) regulates axon growth in vitro and in vivo. Neurobiol Dis 65: 25-34