Uwe Drescher

Uwe Drescher

Professor of Molecular Neurobiology, Group Leader


Uwe Drescher was born in Germany in 1959. He graduated in Biology and Biochemistry at the University of Heidelberg (Germany) in 1986, where he also obtained his Doctoral Degree in 1990 with P. Gruss. He subsequently joined the University of Zurich (Switzerland) as a postdoctoral fellow in the laboratory of H. Möhler. In 1991, he took a group leader position at the Max-Planck-Institute for Developmental Biology (Tübingen, Germany) in the Department of Friedrich Bonhoeffer. In 2000, he took a Senior Lecturer position at the MRC Centre for Developmental Neurobiology, where he was appointed to a Professor for Molecular Neurobiology in 2007.

Uwe Drescher is member of the Faculty1000 for Developmental Neurobiology, committee member of the French ANR, and co-organizes the bi-annual meeting of the ‘Molecular mechanisms of brain wiring’ currently held at the IST (Vienna).


Thompson Reuters Researcher ID: C-5438-2009
KCL PURE: https://kclpure.kcl.ac.uk/portal/uwe.drescher.html

All publications:


Adnan G, Rubikaite A, Khan M, Reber M, Suetterlin P, Hindges R, Drescher U (2020) The GTPase Arl8B plays a principle role in the positioning of interstitial axon branches by spatially controlling autophagosome and lysosome location. J Neurosci (in press)


Ingham NJ, Steel KP, Drescher U (2017) On the role of ephrinA2 in auditory function. Hear Res 350: 11-16


Suetterlin P, Drescher U (2014) Target-independent ephrina/EphA-mediated axon-axon repulsion as a novel element in retinocollicular mapping. Neuron 84: 740-52


Gatto G, Dudanova I, Suetterlin P, Davies AM, Drescher U, Bixby JL, Klein R (2013) Protein tyrosine phosphatase receptor type O inhibits trigeminal axon growth and branching by repressing TrkB and Ret signaling. J Neurosci 33: 5399-410


Suetterlin P, Marler KM, Drescher U (2011) Axonal ephrinA/EphA interactions, and the emergence of order in topographic projections. Semin Cell Dev Biol


Marler KJ, Poopalasundaram S, Broom ER, Wentzel C, Drescher U (2010) Pro-neurotrophins secreted from retinal ganglion cell axons are necessary for ephrinA-p75NTR-mediated axon guidance. Neural Dev 5: 30


Plachez C, Andrews W, Liapi A, Knoell B, Drescher U, Mankoo B, Zhe L, Mambetisaeva E, Annan A, Bannister L, Parnavelas JG, Richards LJ, Sundaresan V (2008) Robos are required for the correct targeting of retinal ganglion cell axons in the visual pathway of the brain. Mol Cell Neurosci 37: 719-30


Carvalho RF, Beutler M, Marler KJ, Knöll B, Becker-Barroso E, Heintzmann R, Ng T, Drescher U (2006) Silencing of EphA3 through a cis interaction with ephrinA5. Nat Neurosci 9: 322-30


Prin F, Ng KE, Thaker U, Drescher U, Guthrie S (2005) Ephrin-As play a rhombomere-specific role in trigeminal motor axon projections in the chick embryo. Dev Biol 279: 402-19


Knöll B, Drescher U (2004) Src family kinases are involved in EphA receptor-mediated retinal axon guidance. J Neurosci 24: 6248-57