Benedikt  Berninger

Benedikt Berninger

Professor of Developmental Neurobiology, Group Leader



Biography:

Benedikt Berninger was born in Munich in 1968. He graduated in Biology from the Ludwig Maximilians University (Munich, Germany) in 1992. He obtained his Doctoral Degree from the same university for work he had conducted at the Max-Planck Institute of Psychiatry (now Neurobiology) in the laboratory of Hans Thoenen. He subsequently joined the University of California in San Diego as a postdoctoral fellow in the laboratory of Mu-ming Poo during which time he was supported by a Human Frontier Science Program (HFSP) Long-term Fellowship. After a brief stay at the Karolinska Institute in the laboratory of Jonas Frisén funded by HFSP, he took a group leader position at the Max Planck Institute of Neurobiology in Munich in 2001. Subsequently he became staff scientist at the Helmholtz Center Munich (2003) in the laboratory of Magdalena Götz. In 2005 he became lecturer at the Institute of Physiology where he habilitated in Physiology in 2011. In 2012 he joined the University Medical Center of the Johannes Gutenberg University as Full Professor. From March 2018 he is Professor of Developmental Neurobiology at the Centre for Developmental Neurobiology at King’s College London and member of the MRC Centre for Neurodevelopmental Disorders.Benedikt is a Wellcome Trust Investigator.

Related News:

The sweet smell of adult neurogenesis

05/02/19
Adult olfactory bulb neurogenesis improves odour distinction

Welcome to two new labs!

02/02/18
Welcome to Adil Khan and Benedikt Berninger labs

All publications:

2019

Bragado Alonso S, Reinert JK, Marichal N, Massalini S, Berninger B, Kuner T, Calegari F (2019) An increase in neural stem cells and olfactory bulb adult neurogenesis improves discrimination of highly similar odorants. EMBO J

2018

Zhao S, Fan W, Guo X, Xue L, Berninger B, Salierno MJ, Del Campo A (2018) Microenvironments to study migration and somal translocation in cortical neurons. Biomaterials 156: 238-247

2017

Dehorter N, Marichal N, Marín O, Berninger B (2017) Tuning neural circuits by turning the interneuron knob. Curr Opin Neurobiol 42: 144-151

2016

Kleiderman S, Gutbier S, Ugur Tufekci K, Ortega F, Sá JV, Teixeira AP, Brito C, Glaab E, Berninger B, Alves PM, Leist M (2016) Conversion of Nonproliferating Astrocytes into Neurogenic Neural Stem Cells: Control by FGF2 and Interferon-?. Stem Cells 34: 2861-2874

2015

Chen G, Wernig M, Berninger B, Nakafuku M, Parmar M, Zhang CL (2015) In Vivo Reprogramming for Brain and Spinal Cord Repair. eNeuro 2(5): 0106-15.20

2014

Heinrich C, Bergami M, Gascón S, Lepier A, Viganò F, Dimou L, Sutor B, Berninger B, Götz M (2014) Sox2-mediated conversion of NG2 glia into induced neurons in the injured adult cerebral cortex. Stem Cell Reports 3: 1000-14

2013

Deshpande A, Bergami M, Ghanem A, Conzelmann KK, Lepier A, Götz M, Berninger B (2013) Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb. Proc Natl Acad Sci U S A 110: E1152-61

2012

Chen X, Lepier A, Berninger B, Tolkovsky AM, Herbert J (2012) Cultured subventricular zone progenitor cells transduced with neurogenin-2 become mature glutamatergic neurons and integrate into the dentate gyrus. PLoS One 7: e31547

2011

Ortega F, Costa MR, Simon-Ebert T, Schroeder T, Götz M, Berninger B (2011) Using an adherent cell culture of the mouse subependymal zone to study the behavior of adult neural stem cells on a single-cell level. Nat Protoc 6: 1847-59

2010

Heinrich C, Blum R, Gascón S, Masserdotti G, Tripathi P, Sánchez R, Tiedt S, Schroeder T, Götz M, Berninger B (2010) Directing astroglia from the cerebral cortex into subtype specific functional neurons. PLoS Biol 8: e1000373

2009

2008

Bergami M, Santi S, Formaggio E, Cagnoli C, Verderio C, Blum R, Berninger B, Matteoli M, Canossa M (2008) Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes. J Cell Biol 183: 213-21

2007

Berninger B, Costa MR, Koch U, Schroeder T, Sutor B, Grothe B, Götz M (2007) Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia. J Neurosci 27: 8654-64

2001

Brünig I, Penschuck S, Berninger B, Benson J, Fritschy JM (2001) BDNF reduces miniature inhibitory postsynaptic currents by rapid downregulation of GABA(A) receptor surface expression. Eur J Neurosci 13: 1320-8

2000

Schinder AF, Berninger B, Poo M (2000) Postsynaptic target specificity of neurotrophin-induced presynaptic potentiation. Neuron 25: 151-63

1999

Berninger B, Schinder AF, Poo MM (1999) Synaptic reliability correlates with reduced susceptibility to synaptic potentiation by brain-derived neurotrophic factor. Learn Mem 6: 232-42