Karen Yap

Karen Yap

Research Associate


Makeyev group

Related News:

Hybridisation-proximity labelling sheds new light on subcellular compartments

04/11/21
New findings from the Makeyev lab

Long noncoding RNAs and their diverse influences

16/10/18
"Meaningless" part of genome has important cellular functions and can promote malignancy

All Publications:

2018

Yap K, Mukhina S, Zhang G, Tan JSC, Ong HS, Makeyev EV (2018) A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival. Mol Cell

2017

Verbeeren J, Verma B, Niemelä EH, Yap K, Makeyev EV, Frilander MJ (2017) Alternative exon definition events control the choice between nuclear retention and cytoplasmic export of U11/U12-65K mRNA. PLoS Genet

2016

Yap K, Xiao Y, Friedman BA, Je HS, Makeyev EV (2016) Polarizing the Neuron through Sustained Co-expression of Alternatively Spliced Isoforms. Cell Rep

2014

Neo WH, Yap K, Lee SH, Looi LS, Khandelia P, Neo SX, Makeyev EV, Su IH (2014) MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression. J Biol Chem

2013

Yap K, Makeyev EV (2013) Regulation of gene expression in mammalian nervous system through alternative pre-mRNA splicing coupled with RNA quality control mechanisms. Mol Cell Neurosci

2012

Yap K, Lim ZQ, Khandelia P, Friedman B, Makeyev EV (2012) Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention. Genes Dev