Ivo Lieberam

Ivo Lieberam

Reader, Group Leader



Biography:

Dr Ivo Lieberam joined King’s College London (KCL) in 2009 and moved to the Centre for Stem Cells and Regenerative Medicine in 2015. During his PhD thesis in Prof Klaus Rajewsky’s group at the Institute for Genetics (University of Cologne, Germany), he studied antigen presenting cells and their communication with T lymphocytes. Then, he shifted his interest to developmental neuroscience and joined the group of Prof Thomas Jessell (Columbia University, New York, USA). In the Jessell group, he investigated the role of the chemokine receptor Cxcr4 in CNS exit point choice, a crucial step in motor axon guidance. Together with Dr Hynek Wichterle, he also developed a method that allows the direct differentiation of motor neurons from embryonic stem cells. This approach has become an important research tool for scientists studying normal motor neuron development and degenerative diseases which affect motor neurons.

Links:

Thompson Reuters Researcher ID: C-5324-2009
KCL PURE: https://kclpure.kcl.ac.uk/portal/ivo.lieberam.html

Related News:

All publications:

2019

2014

Machado CB, Kanning KC, Kreis P, Stevenson D, Crossley M, Nowak M, Iacovino M, Kyba M, Chambers D, Blanc E, Lieberam I (2014) Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons. Development 141: 784-94

2010

Lerner O, Davenport D, Patel P, Psatha M, Lieberam I, Guthrie S (2010) Stromal cell-derived factor-1 and hepatocyte growth factor guide axon projections to the extraocular muscles. Dev Neurobiol 70: 549-564

2009

Tekinay AB, Nong Y, Miwa JM, Lieberam I, Ibanez-Tallon I, Greengard P, Heintz N (2009) A role for LYNX2 in anxiety-related behavior. Proc Natl Acad Sci U S A 106: 4477-82

2005

Huber AB, Kania A, Tran TS, Gu C, De Marco Garcia N, Lieberam I, Johnson D, Jessell TM, Ginty DD, Kolodkin AL (2005) Distinct roles for secreted semaphorin signaling in spinal motor axon guidance. Neuron 48: 949-64

2003

Alferink J, Lieberam I, Reindl W, Behrens A, Weiss S, Hüser N, Gerauer K, Ross R, Reske-Kunz AB, Ahmad-Nejad P, Wagner H, Förster I (2003) Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J Exp Med 197: 585-99

2002

Wichterle H, Lieberam I, Porter JA, Jessell TM (2002) Directed differentiation of embryonic stem cells into motor neurons. Cell 110: 385-97

1999

Lieberam I, Förster I (1999) The murine beta-chemokine TARC is expressed by subsets of dendritic cells and attracts primed CD4+ T cells. Eur J Immunol 29: 2684-94