Jon Clarke

Jon Clarke

Emeritus Professor, Group Leader


Jon Clarke received his PhD at Bristol University after studying the Xenopus embryo spinal cord with Alan Roberts. He then moved to King?s College London to work with Nigel Holder on development and regeneration of the amphibian spinal cord before moving to work with Andrew Lumsden on the rhombomeric organisation of the chick embryo brainstem. In 1994 he took a lectureship in the Anatomy and Developmental Biology department at UCL. In 2000 he changed model system from the chick to the zebrafish embryo in order to take advantage of the superior transparency of the fish embryo to pursue live imaging studies of morphogenesis and neurogenesis in the early vertebrate CNS. His current interests are focussed on the regulation of neuroepithelial cell polarity and remodelling cell shape during neurogenesis. He was Head of Anatomy at King?s College London between 2008 and 2014.


Thompson Reuters Researcher ID: C-5347-2009

Related News:

There’s a time and a place for differentiation

Protrusive activity of newborn neurons organises long-distance pattern of differentiation

All publications:


Folgueira M, Clarke JDW (2024) Telencephalic eversion in embryos and early larvae of four teleost species. Evol Dev 26: e12474


Moore RE, Pop S, Alleyne C, Clarke JDW (2022) Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo. EMBO Rep 23: e52493


Knüfer A, Diana G, Walsh GS, Clarke JD, Guthrie S (2020) Cadherins regulate nuclear topography and function of developing ocular motor circuitry. Elife 9
Symonds AC, Buckley CE, Williams CA, Clarke JDW (2020) Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube. Development 147


Kiecker C, Clarke J, Bell E (2019) Teaching embryology through science fiction and role-play. Med Educ 53: 519
Araya C, Häkkinen HM, Carcamo L, Cerda M, Savy T, Rookyard C, Peyriéras N, Clarke JDW (2019) Publisher Correction: Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate. Sci Rep 9: 7699


McIntosh R, Norris J, Clarke JD, Alexandre P (2017) Spatial distribution and characterization of non-apical progenitors in the zebrafish embryo central nervous system. Open Biol 7(2): 160312


Araya C, Carmona-Fontaine C, Clarke JD (2016) Extracellular matrix couples the convergence movements of mesoderm and neural plate during the early stages of neurulation. Dev Dyn 245: 580-9


Buckley C, Clarke J (2014) Establishing the plane of symmetry for lumen formation and bilateral brain formation in the zebrafish neural rod. Semin Cell Dev Biol 31: 100-5


Girdler GC, Araya C, Ren X, Clarke JD (2013) Developmental time rather than local environment regulates the schedule of epithelial polarization in the zebrafish neural rod. Neural Dev 8: 5