David  Edwards

David Edwards

Chair in Paediatrics and Neonatal Medicine



Biography:

David Edwards is Director of the Centre for the Developing Brain, Professor of Paediatrics and Neonatal Medicine, and Head of the Department of Perinatal Imaging and Health, King?s College London, as well as Consultant Neonatologist, Evelina Children?s Hospital.

He is a Fellow of the Academy of Medical Sciences, a National Institute for Health Research Senior Investigator, Visiting Professor in the Department of Bioengineeing, Imperial College, and recipient of the 2007 Arvo Yllpo Quinquennial International Gold Medal.

He was previously Weston Professor of Neonatal Medicine and Chairman and Head of Department of Paediatrics, Obstetrics and Gynaecology at Imperial College London.

The aim of the Centre for the Developing Brain is to reduce the incidence and severity of neurological impairment caused by problems around the time of birth. We have developed a bench-to-bedside research strategy to investigate the mechanisms of perinatal brain injury in order to find effective therapies, and have developed the first successful treatment for birth asphyxia ? hypothermic neural rescue therapy. We have a dedicated neonatal MRI suite cited in the neonatal intensive care unit of St Thomas' Hospital and use imaging and neuroinformatic analysis to study brain development and damage.

Links:

KCL PURE: https://kclpure.kcl.ac.uk/portal/ad.edwards.html

All publications:

2018

Stolp HB, Ball G, So PW, Tournier JD, Jones M, Thornton C, Edwards AD (2018) Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND). Sci Rep 8: 4011
Campbell H, Eddama O, Azzopardi D, Edwards AD, Strohm B, Rivero-Arias O (2018) Hypothermia for perinatal asphyxia: trial-based quality of life at 6-7 years. Arch Dis Child

2017

Acharya KD, Nettles SA, Sellers KJ, Im DD, Harling M, Pattanayak C, Vardar-Ulu D, Lichti CF, Huang S, Edwards DP, Srivastava DP, Denner L, Tetel MJ (2017) The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent. eNeuro 4
Krishnan ML, Wang Z, Aljabar P, Ball G, Mirza G, Saxena A, Counsell SJ, Hajnal JV, Montana G, Edwards AD (2017) Machine learning shows association between genetic variability in PPARG and cerebral connectivity in preterm infants. Proc Natl Acad Sci U S A 114: 13744-13749

Batalle D, Edwards AD, O'Muircheartaigh J (2017) Annual Research Review: Not just a small adult brain: understanding later neurodevelopment through imaging the neonatal brain. J Child Psychol Psychiatry