David Exposito-Alonso

David Exposito-Alonso

PhD student



Biography:

How do the single functional units of the brain, neurons, develop to form such a complex cytoarchitecture and to enable higher functions such as thoughts and actions? Which developmental programs control the integration of specific neuronal subtypes into neural circuits and their precise synaptic connectivity? These questions fascinate me. In the Marin and Rico Labs, I aim to understand these intricate processes, and the alterations occurring in neurodevelopmental diseases. In particular, I am studying interneuron dysfunction in the cerebral cortex, and the underlying molecular mechanisms, associated with schizophrenia. By combining a variety of approaches including bioinformatics, molecular and cell biology and electrophysiology, I investigate specific genetic perturbations that alter the normal wiring of neural circuits in mouse.

Education & Research training:

- MRes/PhD Programme at the Centre for Developmental Neurobiology, King's College London. MRes rotations in Juan Burrone, Oscar Marin, and Beatriz Rico labs.

- MSc in Neurosciences at the University of Barcelona. Research project in Eduardo Soriano lab.

- BSc in Biology at the University of Alicante.

Links:

ORCID ID: https://orcid.org/0000-0002-4950-2744

Selected publications:

Favuzzi E, Deogracias R, Marques-Smith A, Maeso P, Jezequel J, Exposito-Alonso D, Balia M, Kroon T, Hinojosa AJ, F Maraver E, Rico B (2019) Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits. Science 363: 413-417