Jon Clarke


Jon Clarke received his PhD at Bristol University after studying the Xenopus embryo spinal cord with Alan Roberts. He then moved to King’s College London to work with Nigel Holder on development and regeneration of the amphibian spinal cord before moving to work with Andrew Lumsden on the rhombomeric organisation of the chick embryo brainstem. In 1994 he took a lectureship in the Anatomy and Developmental Biology department at UCL. In 2000 he changed model system from the chick to the zebrafish embryo in order to take advantage of the superior transparency of the fish embryo to pursue live imaging studies of morphogenesis and neurogenesis in the early vertebrate CNS. His current interests are focussed on the regulation of neuroepithelial cell polarity and remodelling cell shape during neurogenesis. He was Head of Anatomy at King’s College London between 2008 and 2014.


Thompson Reuters Researcher ID: C-5347-2009

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Selected publications:

McIntosh R, Norris J, Clarke JD, Alexandre P (2017) Spatial distribution and characterization of non-apical progenitors in the zebrafish embryo central nervous system. Open Biol 7(2): 160312
Buckley CE, Moore RE, Reade A, Goldberg AR, Weiner OD, Clarke JD (2016) Reversible Optogenetic Control of Subcellular Protein Localization in a Live Vertebrate Embryo. Dev Cell 36: 117-26
Araya C, Tawk M, Girdler GC, Costa M, Carmona-Fontaine C, Clarke JD (2014) Mesoderm is required for coordinated cell movements within zebrafish neural plate in vivo. Neural Dev 9: 9
Girdler GC, Araya C, Ren X, Clarke JD (2013) Developmental time rather than local environment regulates the schedule of epithelial polarization in the zebrafish neural rod. Neural Dev 8: 5