Alumnus

Anna Dart

Anna Dart

Research Associate



Biography:

I have two Masters degrees: an MSc in Neuroscience which I carried out at the Institute of Psychiatry, King’s College London and an MRes in Biochemical Research from Imperial College London. One of the projects during my MRes involved studying the signalling pathways that regulate phagocytosis, which I was able to develop into a PhD at Imperial College London in the lab of Dr. Emmanuelle Caron from 2006 to 2010. Following my PhD, I was given the opportunity to be a lead scientist in an interdisciplinary systems biology project modelling the mechanical characteristics of phagocytosis at Imperial College London.

I then moved back to King’s College London in 2010 for my second post-doctoral project studying the role of p21-activated kinase (PAK4) in breast cancer progression. This work established a new kinase-independent function for PAK4 in regulating the protein stability of the unconventional Rho GTPase RhoU and led to publication in the Journal of Cell Biology.

Now in the lab of Professor Gordon-Weeks I am investigating the role of the F-actin binding protein drebrin in both prostate cancer invasion and neuritogenesis.

Links:

ORCID ID: https://orcid.org/0000-0002-2412-3502
KCL PURE: https://kclpure.kcl.ac.uk/portal/anna.dart.html
Research Gate: https://www.researchgate.net/profile/Anna_Dart

Selected publications:

Dart AE, Gordon-Weeks PR (2017) The Role of Drebrin in Cancer Cell Invasion. Adv Exp Med Biol 1006: 375-389
Dart AE, Worth DC, Muir G, Chandra A, Morris JD, McKee C, Verrill C, Bryant RJ, Gordon-Weeks PR (2017) The drebrin/EB3 pathway drives invasive activity in prostate cancer. Oncogene 36: 4111-4123