Development of human neocortex

Selected Publications

Gentile A, Stavropoulou K, Long KR (2025) ECM Mechanics in Central Nervous System Morphogenesis. Dev Neurosci

Long KR, Huttner WB, Namba T (2025) Neocortex Folding in Primates up to Human: Evolution and Mechanisms. Dev Neurosci

Tapia VS, Withers SE, Zhou R, Bennington A, Hoyle C, Hedley F, El Khouja A, Luka N, Massimo M, Crilly S, Long KR, Lawrence CB, Kasher PR (2025) The role of 25-hydroxycholesterol in the pathophysiology of brain vessel dysfunction associated with infection and cholesterol dysregulation. Dis Model Mech

Perochon T, Krsnik Z, Massimo M, Ruchiy Y, Romero AL, Mohammadi E, Li X, Long KR, Parkkinen L, Blomgren K, Lagache T, Menassa DA, Holcman D (2025) Unraveling microglial spatial organization in the developing human brain with DeepCellMap, a deep learning approach coupled with spatial statistics. Nat Commun

Namba T, Dóczi J, Pinson A, Xing L, Kalebic N, Wilsch-Bräuninger M, Long KR, Vaid S, Lauer J, Bogdanova A, Borgonovo B, Shevchenko A, Keller P, Drechsel D, Kurzchalia T, Wimberger P, Chinopoulos C, Huttner WB (2019) Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis. Neuron

Kostic M, Paridaen JTML, Long KR, Kalebic N, Langen B, Grübling N, Wimberger P, Kawasaki H, Namba T, Huttner WB (2019) YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex. Cell Rep

Long K, Moss L, Laursen L, Boulter L, Ffrench-Constant C (2016) Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin. Nat Commun