Synapse formation and autism

Selected Publications

Pérez-Sisqués L, Bhatt SU, Matuleviciute R, Gileadi TE, Kramar E, Graham A, Garcia FG, Keiser A, Matheos DP, Cain JA, Pittman AM, Andreae LC, Fernandes C, Wood MA, Giese KP, Basson MA (2024) The Intellectual Disability Risk Gene Kdm5b Regulates Long-Term Memory Consolidation in the Hippocampus. J Neurosci

Ellingford RA, Tojo M, Basson MA, Andreae LC (2024) Male-Dominant Effects of Chd8 Haploinsufficiency on Synaptic Phenotypes during Development in Mouse Prefrontal Cortex. ACS Chem Neurosci

Ellingford RA, Panasiuk MJ, de Meritens ER, Shaunak R, Naybour L, Browne L, Basson MA, Andreae LC (2021) Cell-type-specific synaptic imbalance and disrupted homeostatic plasticity in cortical circuits of ASD-associated Chd8 haploinsufficient mice. Mol Psychiatry
Armstrong EC, Caruso A, Servadio M, Andreae LC, Trezza V, Scattoni ML, Fernandes C (2020) Assessing the developmental trajectory of mouse models of neurodevelopmental disorders: Social and communication deficits in mice with Neurexin 1α deletion. Genes Brain Behav

Tyson AL, Akhtar AM, Andreae LC (2019) Optimisation and validation of hydrogel-based brain tissue clearing shows uniform expansion across anatomical regions and spatial scales. Sci Rep
Pervolaraki E, Tyson AL, Pibiri F, Poulter SL, Reichelt AC, Rodgers RJ, Clapcote SJ, Lever C, Andreae LC, Dachtler J (2019) The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice Mol Autism
Taylor RD, Heine M, Emptage NJ, Andreae LC (2018) Neuronal Receptors Display Cytoskeleton-Independent Directed Motion on the Plasma Membrane. iScience
Andreae LC, Burrone J (2018) The role of spontaneous neurotransmission in synapse and circuit development. J Neurosci Res

Kathuria A, Nowosiad P, Jagasia R, Aigner S, Taylor RD, Andreae LC, Gatford NJF, Lucchesi W, Srivastava DP, Price J (2018) Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development. Mol Psychiatry

Anderson GW, Deans PJ, Taylor RD, Raval P, Chen D, Lowder H, Murkerji S, Andreae LC, Williams BP, Srivastava DP (2015) Characterisation of neurons derived from a cortical human neural stem cell line CTX0E16. Stem Cell Res Ther
Tyson AL, Hilton ST, Andreae LC (2015) Rapid, simple and inexpensive production of custom 3D printed equipment for large-volume fluorescence microscopy. Int J Pharm
Andreae LC, Burrone J (2015) Spontaneous Neurotransmitter Release Shapes Dendritic Arbors via Long-Range Activation of NMDA Receptors. Cell Rep

Andreae LC, Burrone J (2014) The role of neuronal activity and transmitter release on synapse formation. Curr Opin Neurobiol
Aigner S, Heckel T, Zhang JD, Andreae LC, Jagasia R (2014) Human pluripotent stem cell models of autism spectrum disorder: emerging frontiers, opportunities, and challenges towards neuronal networks in a dish. Psychopharmacology (Berl)
Andreae LC, Fredj NB, Burrone J (2012) Independent vesicle pools underlie different modes of release during neuronal development. J Neurosci
Tossell K, Andreae LC, Cudmore C, Lang E, Muthukrishnan U, Lumsden A, Gilthorpe JD, Irving C (2011) Lrrn1 is required for formation of the midbrain-hindbrain boundary and organiser through regulation of affinity differences between midbrain and hindbrain cells in chick. Dev Biol
Morice E, Andreae LC, Cooke SF, Vanes L, Fisher EM, Tybulewicz VL, Bliss TV (2008) Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome. Learn Mem