Functional analysis of the zebrafish visual system

How is information about the visual scene represented in the brain and how is this information used to drive visual behaviours? What are the genetic and experience-dependent mechanisms that drive assembly of functional neural circuits and the ontogeny of behaviour? To address these questions, we are using zebrafish as a model organism. The brain of the larval zebrafish is small, containing less than 100,000 neurons, but nevertheless supports a rich repertoire of visually-driven behaviours. Furthermore, because larvae are translucent the entire volume of the brain can be imaged non-invasively and with single-neuron resolution.

We use in vivo imaging to study the structure and function of the visual brain at multiple spatial scales - from individual neurons to the entire brain - to reveal the structural and functional development of circuits that control visually driven behaviour.

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