Neuronal circuitries underlying the function of the mammalian cerebral cortex collectively constitute one of the most complex biological systems. As such, unraveling the mechanisms that control their development represents one of the most challenging questions in science. Understanding this process is also an imperative need in biomedicine, because abnormal wiring is thought to cause severe neuropsychiatric disorders, such as autism and schizophrenia. Our goal in the lab is to understand the cellular and molecular mechanisms controlling the development and maturation of neural networks in health and disease.