Synapse formation and autism

Laura Andreae

Reader in Developmental Neuroscience

My lab is interested in how synaptic connections and neuronal circuits are formed during development, and how these processes may be disrupted in neurodevelopmental disorders such as autism and schizophrenia. We use a variety of techniques including electrophysiology, structural and functional imaging in both rodent models and human inducible pluripotent stem cells, to address these questions. We have strong connections with psychiatrists at the Institute of Psychiatry (KCL), working together with clinicians to try to understand the underlying pathophysiology of these disorders, with the eventual goal of finding new treatments.

Related News:

How CHD8 mutations can disrupt ASD-relevant circuits in the cortex 

New paper out now from the Andreae lab