RNA-based regulation of gene expression in neurodevelopment and disease


Eugene Makeyev

Professor

Eukaryotic gene expression is extensively regulated at the RNA level. We study biological functions of alternative pre-mRNA splicing and noncoding RNAs in normal development of the nervous system and in the context of neurodegenerative diseases and cancer. The approaches we use range from RNA biology, various "omic" techniques and bioinformatics to stem cell biology, developmental biology and mammalian genetics.

Related News:

Hybridisation-proximity labelling sheds new light on subcellular compartments

04/11/21
New findings from the Makeyev lab

Gene regulation mechanism impacting diverse neuropathologies uncovered

26/03/21
SFPQ plays key role in neuronal development

Deciphering the tubulin code

24/02/20
Tuba8 has an instructive role in progenitor differentiation